Abstract: Primary and secondary mutations in anaplastic lymphoma kinase (ALK) are oncogenic. Insights into ALK acquired resistance were used to define a drug design strategy that led to the discovery […]
"Switches, sensors, and new shapes: from design of new functions to cellular consequences of allostery"
“Multidisciplinary (mission directed) research in nanotechnology at the University of Sydney”
"Structural Evidence for Dynamic Nitrogenase Metalloclusters" Abstract: Nitrogenase catalyzes dinitrogen reduction to ammonia and is the only enzyme capable of supplying the world with a reduced form of ‘N’ that […]
Abstract: SARS-CoV2, the causative agent of the COVID-19 pandemic, is an RNA virus that has efficient human to human transmission and carries significant morbidity and mortality for vulnerable patient populations. […]
"Metabolic control of post-translational modifications"
First-Principles Materials Prediction: From Sustainability to the Quantum Information Age Theory-guided materials design is vital to the advancement of sustainability and quantum information science. First-principles theory entirely based on quantum […]
The NSF Center for Integrated Catalysis is delighted to announce that it will be hosting a monthly webinar series. The next webinar of this series will be held on Tuesday, […]
Abstract: Prostaglandin E2 promotes tissue repair and regeneration in multiple tissues. Small molecule inhibitors of the PGE2-degrading enzyme, 15-prostaglandin dehydrogenase, could elevate PGE2 levels in vivo with applications in multiple […]
“Rubbery Electronics” Abstract: Seamlessly merging electronics with biology is of imminent importance in addressing grand societal challenges in health and joy of living. However, the main challenge lies in the […]
Cancelled “Tuning the Excitonic Properties of 2-Dimensional Molecular Aggregates across the Visible and Shortwave Infrared” Molecular aggregates are non-covalent self-assemblies of chromophores wherein transition dipole moments of individual molecules couple […]
“De novo design of function in water-soluble and membrane proteins”
