Special Biochem Seminar – Jie Zhou
Mani L. Bhaumik Centennial Collaboratory 607 Charles E. Young Dr., East, Los Angeles, CATitle: Identify and Target Proteolytic Neoepitopes in Cancer
Title: Identify and Target Proteolytic Neoepitopes in Cancer
Prof. Bozovic Flyer Title: Physics of the Auditory System Abstract: Hair cells of the auditory system constitute a remarkable biological sensor that exhibits nanometer-scale sensitivity of mechanical detection. Our experiments explore the active nonlinear processes behind the detection of very weak signals. We demonstrate the presence of chaos in the innate motility of active bundles, and […]
Tales in Molecular Evolution: From Chiral Symmetry Breaking to New-to-Nature Biocatalysis The evolutionary journey of chemistry on our planet, from small molecules to genetic polymers, presents fascinating opportunities for the organic chemist. At one end, mysterious early steps evoke grand questions at the foundations of chemistry, while at the other, biology’s extraordinary machinery lies primed for creative manipulation. […]
Prof. Wickens Flyer Selective Synthesis via Light and Electricity Abstract: We are investigating how organic radical ions–typically thought of as fleeting intermediates–can be tamed and exploited as a new family of organocatalysts and small molecule reagents. We identified selective generation of such species as a key hurdle stymying exploration these electronically-destabilized systems. To address this […]
Flyer: Zhipeng Lu Flyer Title: What does RNA look like in cells? Structures, interactions and modifications. Abstract: RNA in living cells are in constant motion, form dynamic structures, and interact with many molecules, including other RNAs. Direct determination of RNA structures and interactions in vivo is essential to understanding their functions, and developing new RNA-based […]
Title: TBA Abstract: TBA
Prof Ginger Flyer Title: Probing Ion Injection and Transport in Conjugated Polymers: From Bioelectronic Brains to Energy Storage Abstract: Ion injection and transport in conjugated polymers affects the performance of devices ranging from organic electrochemical transistors (OECT) for bioelectronic signal transduction, and from aqueous polymer batteries to next generation neuromorphic computing architectures. The performance of conjugated […]
Title: Stereoselective Cationic Polymerization of Prochiral Monomers Abstract: The stereochemistry of vinyl polymers, known as polymer tacticity, is intimately linked to their resultant material properties. Despite the well-developed stereoselective methods for the polymerization of propylene and other nonpolar -olefins, general approaches to the stereoselective polymerization of polar vinyl monomers are not well developed. In this […]
Prof Ball Flyer Unlocking Fluorine: Activation of Sulfur(VI) Fluorides for New Sulfur-Fluorine Exchange (SuFEx) Reactions Abstract: Sulfur-fluoride exchange (SuFEx) chemistry is emerging as a promising synthetic tool in chemical biology, material science, and synthetic chemistry. In synthesis, sulfur (VI) fluorides show unique promise as synthons in organic chemistry due their stability versus other sulfur (VI) […]
Title: TBD Abstract: TBD