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Biochemistry Seminar Series – Prof. Francesca M. Marassi

Biochemistry, Seminars

March 17, 2023 3:30 pm - 4:30 pm
Mani L. Bhaumik Centennial Collaboratory
607 Charles E. Young Dr., East
Los Angeles, CA 90095 United States


Francesca Marassi Flyer (1)

Title: Calcification of protein-lipid assemblies in macular degeneration: Insights from NMR

Abstract: The ectopic deposits that form in age-related diseases, like macular degeneration, are rich in lipids and proteins involved in innate immunity, and this has been proposed to reflect an immune response to yet unidentified stress cues. Biomolecular NMR spectroscopy, combined with other biophysical methods and functional assays, can provide insights to the molecular interactions and mechanism for calcified deposit formation.