Cryo-EM structure of TGFBIp fibrils driven by a corneal dystrophy-linked mutation enables design of peptide inhibitors of aggregation

2026-09-08 | Cryo-EM structure of TGFBIp fibrils driven by a corneal dystrophy-linked mutation enables design of peptide inhibitors of aggregation – Proc. Natl. Acad. Sci. U. S. A. Jiang, Y. X.; Salwinski, L.; Sawaya, M. R.; Ge, P.; Lutter, L.; Cheng, X.; Hu, C. J.; Hernandez, H.; Boyer, D. R.; Wang, C.; Melo, F. A.; Cascio, D.; Eisenberg,^* D. S.