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Houk-Jung Organic Colloquium 247: Tehshik Yoon

Organic Colloquium

When
January 19, 2023 4:00 pm - 5:00 pm
Where
Mani L. Bhaumik Centennial Collaboratory
607 Charles E. Young Dr., East
Los Angeles, CA 90095 United States
Speaker Prof. Tehshik Yoon
Attachments

Description

Prof. Yoon Flyer

Stereocontrol in Photochemical Synthesis

Abstract: Photochemistry is intriguing as a synthetic tool because the absorption of light by an organic molecule results in the formation of exceptionally energetic reactive intermediates that can react in ways that are inaccessible to ground-state molecules. However, this high reactivity is also a challenge for stereoselective synthesis: control over the stereochemistry of photochemical reactions, particularly using enantioselective catalysts, has been a long-standing challenging synthetic problem with few general solutions. We recently developed a strategy that utilizes privileged chiral Br√łnsted acid scaffolds to control both the absolute and relative stereochemistry of complex [2+2] photocycloadditions. These reactions have enabled a general, concise, and stereocontrolled¬† strategy for the synthesis of the truxinate and truxillate natural products.

Prof. Tehshik Yoon

Organic Colloquium

Department of Chemistry

University of Wisconsin-Madison

Attachments: