Loading Events

Distinguished Lecture Series – David A. Leigh

Distinguished Lecture Series

January 25, 2024 4:00 pm - 5:00 pm
Mani L. Bhaumik Centennial Collaboratory
607 Charles E. Young Dr., East
Los Angeles, CA 90095 United States
Speaker Professor David A. Leigh


Title: Giving Chemistry Direction

Abstract: In recent years examples of synthetic molecular machines and motors have been developed, all be they primitive by biological standards. Such molecules are best designed to work through statistical mechanisms. In a manner reminiscent of Maxwell’s Demon, random thermal motion can be rectified through ratchet mechanisms, giving chemistry direction.

It is increasingly being recognized that similar concepts can be applied to other chemical exchange processes. Ratchet mechanisms—effectively chemical engines in which catalysis of ‘fuel’ to ‘waste’ is used to drive another chemical process—can cause directional impetus in what are otherwise stochastic systems, including reversible chemical reactions. This is ushering in a new era of non-equilibrium chemistry, providing fundamental advances in functional molecule design and the first examples of molecular robotics, overturning existing dogma and offering fresh insights into biology and molecular nanotechnology.

David Leigh DLS Flyer

Professor David A. Leigh

Distinguished Lecture Series

Department of Chemistry
The University of Manchester