Chem 228: Michelle Y. Simmons, Ph.D.
“Engineering qubits in silicon with atomic precision”
Loading view.
Special Bio-Inorganic Chemistry Seminar
“Tuning the Reactivity Landscape of Metalloenzymes: From Active Site Modifications to Long-range Dynamic Effects” Abstract: Metalloenzymes rely on transition metals within the protein scaffold to perform a wide variety of molecular […]
Expanding the genetic code – new chemistries in living system
Abstract: Nature uses a limited set of twenty amino acids to synthesize proteins. In recent years it has become possible to site-specifically incorporate designer amino acids with tailored chemical properties […]
Chem 268: Prof. Elizabeth Villa
"Opening Windows into the Cell: Bringing Structure to Cell Biology Using Cryo-electron Tomography"
NSF Center for Integrated Catalysis Webinar Series
The NSF Center for Integrated Catalysis is delighted to announce that it will be hosting a monthly webinar series. The next webinar of this series will be held on Tuesday, […]
Special Bio-Inorganic Chemistry Seminar
"Chemical and Biological Design Approaches to Controlling Protons, Electrons, and Substrates for Sustainable Catalysis" Abstract: The reductive transformation of small molecules into value-added products represents an attractive way to store sustainable […]
Novel GABA- and Ornithine Aminotransferase Inactivators and Potential New Treatments for Epilepsy, Addiction, Neuropathic Pain, and Hepatocellular Carcinoma
Abstract: An imbalance in the levels of the inhibitory neurotransmitter g-aminobutyric acid (GABA) and the excitatory neurotransmitter L-glutamate can lead to convulsions. Inhibition of g-aminobutyric acid aminotransferase (GABA-AT), the enzyme […]
Theoretical Physical Chemistry Seminar – Dr. Bingqing Cheng, Cambridge
Predicting material properties with the help of machine learning A central goal of computational physics and chemistry is to predict material properties using first-principles methods based on the fundamental laws […]
Theoretical Physical Chemistry Seminar – Dr. Henrik Larsson, Caltech
Molecules in quantum motion In order to fully understand the nature of chemical reactions and molecular properties, we need to simulate both the electronic and vibrational motion quantum mechanically. However, […]
Special Bio-Inorganic Chemistry Seminar
“ Exploring Metalloenzymes for Therapeutics and Sustainable Catalysis” Abstract: Metalloenzymes are at the heart of numerous biological processes ranging from respiration and photosynthesis to natural product biosynthesis. Research in the […]
Prioritizing the patient – The discovery of lorlatinib, a macrocyclic ALK inhibitor for the treatment of resistant and metastatic NSCLC
Abstract: Primary and secondary mutations in anaplastic lymphoma kinase (ALK) are oncogenic. Insights into ALK acquired resistance were used to define a drug design strategy that led to the discovery […]