Title: Anaerobic Heteroatom Transfer Reactions Promoted by Photoexcited 1,3-Dipoles Abstract: Heteroatom units, such as carbonyls, alcohols, and amines, are prevalent motifs in many medicinally important compounds. Methods to incorporate these […]
Title: Development of Allosteric Inhibitors of VCP/ p97 to Interrogate Novel Biology and Fuel Cancer Drug Discovery Abstract: Clinical success in targeting the protein degradation pathway using proteasome inhibitors has […]
Title: Catalytic strategies for the selective construction of sp3-rich organic scaffolds Abstract: The topological complexity of sp3-rich scaffolds imparts specific beneficial properties into organic small molecules and enables refined tuning […]