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- 1951-1953
Jerome Aaron Scholarship
- 1957-1958
Union Carbide Fellow
- 1958-1959
Fulbright Scholar
- 1980
Herbert Newby McCoy Award
- 1983
Fellow, American Physical Society
- 1983
UCLA Alumni Association Distinguished Teaching Award
- 1990
Alexander von Humboldt Senior Award, University of Mainz
- 1997
UCLA College of Letters and Science Faculty Award
- 1998
Alexander von Humboldt Senior Award, Max Planck Institute, Potsdam
- 2000
Kolthoff Lecturer, University of Minnesota
- 2002
American Chemical Society Award in Colloid Chemistry
Representative Publications
- Knobler, C. M., Gelbart, W. M. (2022) How and why RNA genomes are (partially) ordered in viral capsids. Curr. Opin. Virol. 52:203-210.
- Tanimoto, C. R., Thurm, A. R., Brandt, D. S., Knobler, C. M., Gelbart, W. M. (2022) The Nonmonotonic Dose Dependence of Protein Expression in Cells Transfected with Self-Amplifying RNA. J. Virol. 96 (7). doi: 10.1128/jvi.01858-21
- Duran-Meza, A. L., Villagrande-Escareno, M. V., Ruiz-Garcia, J., Knobler, C. M., Gelbart, W. M. (2021) Controlling the surface charge of simple viruses. PLoS ONE, 16(9): e0255820.
- Beren, C., Cui, Y., Chakravarty, A., Yang, X., Knobler, C. M, Zhou, Z. H., Gelbart, W. M. (2020) Genome organization and interaction with capsid protein in a multipartite RNA virus. PNAS, 117 (20), 10673-80.
- Thurm, A. R., Beren, C., Duran-Meza, A. L., Knobler, C. M., Gelbart, W. M. (2019) RNA homopolymers form higher-curvature virus-like particles than do normal-composition RNAs. Biophysical Journal, 117 (7), 1331-41.
- Chung, S., Lerner, E., Jin, Y., Kim, S., Alhadid, Y., Grimaud, L. W., Zhang, I. X., Knobler, C. M., Gelbart, W. M., Weiss, S. (2019) The effect of macromolecular crowding on single-round transcription by Escherichia coli RNA polymerase. Nucleic Acids Research, 47 (3), 1440-50.
- Biddlecome, A., Habte, H. H., McGrath, K. M, Sambanthamoorthy, S., Wurm, M., Sykora, M. M., Knobler, C. M., Lorenz, I. C., Lasaro, M., Elbers, K., Gelbart, W. M. (2019) Delivery of self-amplifying RNA vaccines in in vitro reconstituted virus-like particles. PLoS ONE, 14 (6): e0215031.
- Beren, C. B., Liu, K. N., Dreesens, L. L., Knobler, C. M., Gelbart, W. M. (2018) Enzymatic Synthesis and Fractionation of Fluorescent PolyU RNAs. Bio-protocols, 8 (17) e2988.
- Garmann R. F., Knobler C. M., Gelbart W. M. (2018) Protocol for Efficient Cell-Free Synthesis of Cowpea Chlorotic Mottle Virus-Like Particles Containing Heterologous RNAs. In: Wege C., Lomonossoff G. (eds) Virus-Derived Nanoparticles for Advanced Technologies. Methods in Molecular Biology, vol 1776. Humana Press, New York, NY
- Chen, Y. J., Wu, D., Gelbart, W. M., Knobler, C. M., Phillips, R., Kegel, W. K. (2018) Two-Stage Dynamics of In Vivo Bacteriophage Genome Ejection. Phys. Rev. X, American Physical Society, 8, 021029.
- Beren, C., Dreesens, L. L., Liu, K. N., Knobler, C. M., & Gelbart, W. M. (2017). The effect of RNA secondary structure on the self-assembly of viral capsids. Biophysical journal, 113, 339-347.
- Garmann, R. F., Gopal, A., Athavale, S. S., Knobler, C. M., Gelbart, W. M., & Harvey, S. C. (2015). Visualizing the global secondary structure of a viral RNA genome with cryo-electron microscopy. Rna, 21(5), 877-86.
- Garmann, R. F., Comas-Garcia, M., Knobler, C. M., & Gelbart, W. M. (2015). Physical principles in the self-assembly of a simple spherical virus. Accounts of chemical research, 49, 48-55.
- Jin, Y., Sdao, S. M., Dover, J. A., Porcek, N. B., Knobler, C. M., Gelbart, W. M., & Parent, K. N. (2015). Bacteriophage P22 ejects all of its internal proteins before its genome. Virology, 485, 128-134.
- Singaram, S. W., Garmann, R. F., Knobler, C. M., Gelbart, W. M., & Ben-Shaul, A. (2015). Role of RNA branchedness in the competition for viral capsid proteins. The Journal of Physical Chemistry B, 119, 13991-14002.
- Jin, Y., Knobler, C. M., & Gelbart, W. M. (2015). Controlling the extent of viral genome release by a combination of osmotic stress and polyvalent cations. Physical Review E, 92, 022708.
- Garmann, R. F., Sportsman, R., Beren, C., Manoharan, V. N., Knobler, C. M., & Gelbart, W. M. (2015). A simple RNA-DNA scaffold templates the assembly of monofunctional virus-like particles. Journal of the American Chemical Society, 137, 7584-7587.
- Gopal, A., Egecioglu, D. E., Yoffe, A. M., Ben-Shaul, A., Rao, A. L., Knobler, C. M., & Gelbart, W. M. (2014). Viral RNAs are unusually compact. PLoS One, 9, e105875.
- Comas-Garcia, M., Garmann, R. F., Singaram, S. W., Ben-Shaul, A., Knobler, C. M., & Gelbart, W. M. (2014). Characterization of viral capsid protein self-assembly around short single-stranded RNA. The Journal of Physical Chemistry B, 118, 7510-7519.
- Garmann, R. F., Comas-Garcia, M., Koay, M. S., Cornelissen, J. J., Knobler, C. M., & Gelbart, W. M. (2014). The role of electrostatics in the assembly pathway of a single-stranded RNA virus. Journal of virology, JVI–01044.
- Garmann, R. F., Comas-Garcia, M., Gopal, A., Knobler, C. M., & Gelbart, W. M. (2014). The assembly pathway of an icosahedral single-stranded RNA virus depends on the strength of inter-subunit attractions. Journal of molecular biology, 426, 1050-1060.
- Vega-Acosta, J. R., Cadena-Nava, R. D., Gelbart, W. M., Knobler, C. M., & Ruiz-Garcı́a, J. (2014). Electrophoretic mobilities of a viral capsid, its capsid protein, and their relation to viral assembly. The Journal of Physical Chemistry B, 118, 1984-1989.
- Azizgolshani, O., Garmann, R. F., Cadena-Nava, R., Knobler, C. M., & Gelbart, W. M. (2013). Reconstituted plant viral capsids can release genes to mammalian cells. Virology, 441, 12-17.
- Cadena-Nava, R. D., Comas-Garcia, M., Garmann, R. F., Rao, A. L., Knobler, C. M., & Gelbart, W. M. (2012). Self-assembly of viral capsid protein and RNA molecules of different sizes: requirement for a specific high protein/RNA mass ratio. Journal of virology, 86, 3318-3326.
- Gopal, A., Zhou, Z. H., Knobler, C. M., & Gelbart, W. M. (2012). Visualizing large RNA molecules in solution. Rna, 18, 284-299.
- Comas-Garcia, M., Cadena-Nava, R. D., Rao, A. L., Knobler, C. M., & Gelbart, W. M. (2012). In vitro quantification of the relative packaging efficiencies of single-stranded RNA molecules by viral capsid protein. Journal of virology, JVI–01695.
- Snyder, J. E., Azizgolshani, O., Wu, B., He, Y., Lee, A. C., Jose, J., Suter, D. M., Knobler, C. M., Gelbart, W. M., Kuhn, R. J. (2011). Rescue of Infectious Particles from Pre-assembled Alphavirus Nucleocapsid Cores. Journal of virology.
- Cadena-Nava, R. D., Hu, Y., Garmann, R. F., Ng, B., Zelikin, A. N., Knobler, C. M., & Gelbart, W. M. (2011). Exploiting fluorescent polymers to probe the self-assembly of virus-like particles. The Journal of Physical Chemistry B, 115, 2386-2391.
- Qiu, X., Rau, D. C., Parsegian, V. A., Fang, L. T., Knobler, C. M., & Gelbart, W. M. (2011). Salt-dependent DNA-DNA spacings in intact bacteriophage λ reflect relative importance of DNA self-repulsion and bending energies. Physical review letters, 106, 028102.
- Prinsen, P., Schoot, P., Gelbart, W. M., & Knobler, C. M. (2010). Multishell structures of virus coat proteins. The Journal of Physical Chemistry B, 114, 5522-5533.
- Knobler, C. M., & Gelbart, W. M. (2010). What Determines the Size of an RNA Virus? In Emerging Topics in Physical Virology (pp. 185-215). World Scientific.
- Knobler, C. M., & Gelbart, W. M. (2009). Physical chemistry of DNA viruses. Annual review of physical chemistry, 60, 367-383.
- Gelbart, W. M., & Knobler, C. M. (2009). Pressurized viruses. Science, 323, 1682-1683.
- Prinsen, P., Fang, L. T., Yoffe, A. M., Knobler, C. M., & Gelbart, W. M. (2009). The force acting on a polymer partially confined in a tube. The Journal of Physical Chemistry B, 113, 3873-3879.
- Lavelle, L., Gingery, M., Phillips, M., Gelbart, W. M., Knobler, C. M., Cadena-Nava, R. D., Vega-Acosta, J. R., Pinedo-Torres, L. A., Ruiz-Garcia, J. (2009). Phase diagram of self-assembled viral capsid protein polymorphs. The Journal of Physical Chemistry B, 113, 3813-3819.
- Yoffe, A. M., Prinsen, P., Gopal, A., Knobler, C. M., Gelbart, W. M., & Ben-Shaul, A. (2008). Predicting the sizes of large RNA molecules. Proceedings of the National Academy of Sciences.
- Chang, C. B., Knobler, C. M., Gelbart, W. M. and Mason, T. G. Curvature Dependence of Viral Protein Structures on Encapsidated Nanoemulsion Droplets, ACS Nano, 2008; 2: 281-6.
- Evilevitch, A., Fang, L.-T., Yoffe, A. M., Castelnuovo, M., Rau, D. C., Parsegian, Gelbart W. M. and Knobler,. C. M. Effects of Salt Concentrations and Bending Energy on the Extent of Ejection of Phage Genomes, Biophys. J., 2008; 94: 1110-20.
- Hu, Y., Zandi, R., Anavitarte, A. Knobler, C. M. and Gelbart, W. M. Packaging of a Polymer by a Viral Capsid: The Interplay Between Polymer Length and Capsid Size, Biophys. J., 2008; 94: 1428-36.
- Gelbart, W. M. and Knobler, C. M. The Physics of Phage, Physics Today, 2008; 61: 42-54.
- W. S. Klug, R. F. Bruinsma, J.-P. Michel, C. M. Knobler, I. L. Ivanovska, C. F. Schmidt and G. J. L. Wuite Failure of Viral Shells, Phys. Rev. Lett., 2006; 97: 228101-4.
- Michel, J.P., Ivanovska, I.L., Gibbons, M. M., W. Klug, W. S., Knobler, C. M.,.Wuite, G. J. L., and Schmidt, C., F. Nanoindentation studies of full and empty viral capsids and the effects of capsid protein mutations on elasticity and strength, Proc. Natl. Acad. Sci (USA), 2006; 103: 430-6.
- Grayson, P., Evilevitch, A., Inamdar, M. M., Purohit, P. K., Gelbart, W. M., Knobler, C. M. and Phillips, R. The effect of genome length on ejection forces in bacteriophage lambda, Virology, 2006; 348: 3845-8.
- Evilevitch, A., Gober, J. W., Phillips, M., Knobler, C. M. and Gelbart, W. M. Measurements of DNA lengths remaining in a viral capsid after osmotically suppressed partial ejection, Biophys. J., 2005; 88: 751-6.
- Evilevitch, A. , Castelnovo, M., Knobler, C. M., and Gelbart, W. M. Measuring the Force Ejecting DNA from Phage, J. Phys. Chem. B, 2004; 108: 6838-43.
- Evilevitch, A., Lavelle, L., Knobler, C. M., Raspaud, E. and Gelbart, W. M. Osmotic pressure inhibition of DNA ejection from phage, Proc. Nat. Acad. Sci. (USA), 2003; 100: 9292-9295.
