Imaging, Learning, and Engineering of Soft Matter Systems at the Nanoscale The motion and dynamics of nanoparticles and macromolecules in bulk and at interfaces is of fundamental importance in physics, chemistry, and biology. Liquid phase transmission electron microscopy (LPTEM) is an emerging technique which enables nanoscale visualization of the motion and dynamics of single nanoparticles […]
“Multicellular Circuit Design”
The NSF Center for Integrated Catalysis is delighted to announce that it will be hosting a monthly webinar series. The next webinar of this series will be held on Tuesday, February 8th, 2022 at 12:30 PM. We are pleased to invite all students, postdocs, faculty, and staff.
“Iron and Copper Active Sites in Porous Materials and Their Correlation to Metalloenzymes”
Abstract: Radical chemistry is an important class of reactions in modern organic synthesis, due to the high reactivity and versatile bond formation and cleavage events that can happen with radical intermediates. One of the current challenges in radical chemistry is to generate these reactive open-shell intermediates from accessible starting materials under mild conditions. We have […]
"Macroscopic Materials from Nanoparticle Assembly"
Stories of Coherence: From Vibronic to Electronic Phenomena A robust understanding of chemical reactivity in excited states is essential for designing and discovering new ways of harnessing energy flow at the atomic and molecular level. Photo-induced coherent processes, which utilize atomic or molecular motions moving with a well-defined phase relationship, may enhance control over important […]
Abstract: The seminar will describe our efforts towards the development of scalable, mild, and general electrosynthetic methodologies for C–C and C–N/X coupling reactions. These electrosynthetic methodologies are largely possible because of a synergy between redox-active mediators developed by the energy storage community and transition metal catalysts. It will be shown that yields from electrocatalytic reactions […]
"Untangling Amyloid: Slowing the Progression of Type 2 Diabetes"
“Self-assembly of colloidal diamond for photonics”
Abstract: Our laboratory focuses on the development of small molecule ligands and enzymatic inhibitors of proteins that interact with nucleic acids. We utilize biophysical and biochemical assays to screen chemical libraries to discover protein-binding ligands, which are then optimized using iterative rounds of molecular design, synthesis, and biological evaluation. Our overarching goals are to develop […]
Abstract: The indole diterpenoids constitute a family of natural products that exhibit potent and selective Big Potassium (BK) ion channel inhibition. We have developed a unified synthetic strategy towards the indole diterpenoid class, culminating in the total synthesis of several representative congeners, including paspaline A and emindole PB. Density functional theory calculations are utilized to […]
