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Houk-Jung Organic Colloquium 247: Sidney Wilkerson-Hill

Mani L. Bhaumik Centennial Collaboratory 607 Charles E. Young Dr., East, Los Angeles, CA

Seminar Sponsored by Organization for Cultural Diversity in Science Prof Wilkerson Hill Flyer Title: Orphaned Cyclopropanes Abstract: Cyclopropanes are strained carbocycles that have fascinated chemists for decades with many established methods for their construction. Unfortunately, many methods struggle to build cyclopropanes containing only alkyl functionality, which limits access to antiviral medicines (e.g., nirmatrelvir), pyrethroid insecticides […]

Inaugural Dickerson Lecture Biochemistry Seminar Series: Robert M. Stroud

Boyer 159 611 Charles E Young Dr E, Los Angeles, CA 90095, Los Angeles, CA

Flyer: Dickerson Lecture Flyer - Robert M. Stroud Title: “Caught in the Act! - Building the Wall!" Abstract: From the atomic structure of the first protein, Myoglobin in which Richard Dickerson played the key role(1), proteins were necessarily purified from large animals. Now complex machines can be 'tagged' and purified endogenously from cells growing under […]

Jeffrey I. Zink Inorganic Chemistry Seminar Series: Mahdi Abu-Omar

Mani L. Bhaumik Centennial Collaboratory 607 Charles E. Young Dr., East, Los Angeles, CA

Flyer: Prof. Mahdi Abu-Omar Flyer Meet the Speaker: 11 a.m., YH 3096 Title: Bifunctional catalysis for upcycling of polyethylene to alkylaromatics Abstract: The current scale of plastics production (nearing 400 million tons per year) and the accompanying waste disposal problems represent a largely untapped opportunity for chemical upcycling. Tandem catalytic conversion by platinum supported on […]

Special Biochem Seminar – Steve Bonilla

Mani L. Bhaumik Centennial Collaboratory 607 Charles E. Young Dr., East, Los Angeles, CA

Title: Dissecting Dynamic RNA 3D Landscapes by Cryo-EM

Houk-Jung Organic Colloquium 247: Dr. Saki Ichikawa

Mani L. Bhaumik Centennial Collaboratory 607 Charles E. Young Dr., East, Los Angeles, CA

Dr. Ichikawa Flyer Title: Natural Recognition Motifs for the E3 Ligase Adapter Cereblon Abstract: Understanding the biology of drug target proteins is essential to enhance drug discovery efforts and mechanistic studies. The clinical drugs thalidomide and its derivatives, known as immunomodulatory drugs (IMiDs), are recognized by a conserved binding domain on the E3 ligase adapter […]

Special Biochemistry Seminar – Michael Lawson

Mani L. Bhaumik Centennial Collaboratory 607 Charles E. Young Dr., East, Los Angeles, CA

Michael Lawson Seminar Title: Defining the Pathways of Eukaryotic Translational Quality Control Abstract: My research examines how protein synthesis concludes on normal and defective mRNAs. Understanding how these processes are choregraphed is crucial for human health; for example, 11% of all heritable human diseases are caused by premature stop codons. As a postdoctoral fellow, I […]

Special Houk-Jung Organic Colloquium 247: Dr. Masha Elkin

Mani L. Bhaumik Centennial Collaboratory 607 Charles E. Young Dr., East, Los Angeles, CA

Abstract: The synthesis of natural products is motivated by their potent biological effects, enigmatic biosynthetic origins, and complex molecular structures. Computational tools such as density functional theory and machine learning can provide mechanistic insights and predict reactivity in silico to inform synthetic campaigns. In addition, computational tools and predictive analytics can guide the development and application […]