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Combining Theory and Experiment to Develop Selective Three-Component Fe-Catalyzed Radical Cascade/Cross-Couplings

Abstract: Despite advances in high-throughput screening methods leading to a surge in the discovery of catalytic reactions, our knowledge of the molecular-level interactions in the rate- and selectivity-determining steps of catalytic reactions, especially those involving highly unstable and reactive open-shell intermediates, is rudimentary. These knowledge gaps prevent control, suppression or enhancement, of competing reaction channels that […]

Chem 218: Prof. Vanessa Wood

“Structure and Surfaces at the Nanoscale”  Abstract: Liquid-phase and wet-processing techniques offer tremendous opportunities for low-cost manufacturing and enable the concept of large-scale nanotechnology. Today, these approaches have facilitated the massive upscaling of lithium ion battery technology and promise to play a future role in a wide variety of electronic, photonic, and electrochemical systems. Materials and […]

Development of New Chemical Platforms for Polymer Synthesis

Abstract: Synthetic polymers have permeated nearly every facet of modern life. From the ubiquity of polyolefins to recent advancements in 3-D printing, organic materials continue to shape the world around us. While tremendous accomplishments have been made with relatively few polymer families, the future requires the development of materials with increased control over structure to produce […]

NSF Center for Integrated Catalysis Webinar Series

The NSF Center for Integrated Catalysis is delighted to announce that it will be hosting a monthly webinar series. The second day of this series will be held on Tuesday, November 17th at 1:00 PM.  We are pleased to invite all students, postdocs, faculty, and staff.

Midstream Presentation: Carter Lantz

Carter Lantz Loo Group “Mass Spectrometry Analysis of Amyloid Proteins and their Interaction with the Aggregation Inhibiting Compound CLR01”

Chem 278: Prof. Caroline Saouma

“Thermodynamic and Mechanistic Studies of C02Reduction Catalysts” Abstract: The increase in global energy demands, coupled with growing environmental concerns, necessitates the development of viable technologies to store solar energy. Towards this end, my group is focused on developing efficient catalysts that convert CO2 to CO, methanol or formic acid. My talk will first describe our […]

Writing the rules for targeting dynamic proteins

Abstract: Transcriptional coactivators and their partner transcription factors have been labeled as intrinsically disordered, fuzzy, and undruggable. We propose that the identification of conserved mechanisms of engagement between coactivators and their cognate activators should provide general principles for small-molecule modulator discovery. Towards that end, biophysical characterization of the structurally divergent coactivator Med25 reveals that it forms […]