“An Organometallic Approach to the Assembly of Atomically Precise Nanomaterials” Abstract: There is significant interest in the ability to build atomically precise nanocluster molecules with complex three-dimensional structures resembling the intricate molecular architectures found in natural systems. We have developed a platform to access a class of robust, well-defined, three-dimensional hybrid nanomolecules with high tunability […]
“Rewriting the Rules of Heterogeneous Catalysis for Supported Subnanometer Metal Cluster Catalysts” Advisor: Professor Anastassia Alexandrova
Abstract: The process development of a BACE-1 inhibitor is described. In order to address major safety and scalability limitations in the Discovery synthesis, two novel reactions were developed. The discovery, development, and scale-up of these reactions will be described. Several additional methodologies which emerged during process research will also be presented.
Abstract:The selective introduction of functional groups at the positions of typically unreactive C-H bonds has been a longstanding challenge in catalysis. To this end, our group has developed practical methods for the catalytic functionalization of C-H bonds with main group reagents.(1-4) These studies have led us to a general strategy of installing a single transient […]
"Simulating linear and nonlinear optical spectra for chromophores in the condensed phase"
Panelist: Prof. Jennifer Casey Dept. of Chemistry and Biochemistry University of California, Los Angeles & Prof. Jay Foley Dept. of Chemistry William Paterson University & Prof. Jacob Olshansky Dept. of Chemistry Amherst College
Evan Maltz Wollman Group “Phenotypic Consequences of Gene Expression Variability”
“Imagining, Building, and Understanding the Next Generation Battery” Abstract: Electrochemical energy conversion and storage is critical for vehicle electrification and storing clean energy from intermittent sources (i.e. wind, solar) on the grid. Towards these goals, my group pursues the broad spectrum of stages necessary for technological innovation: (1) developing new tools to discover fundamental understandings, […]
Abstract:The potential to use mechanochemistry, either in isolated polymers or in polymeric materials, to trigger a programmed, desirable covalent molecular response was first revealed only a decade or so ago. Since that time, covalent polymer mechanochemistry has undergone a renaissance in which it has been extensively explored by a number of research groups and for a variety of purposes including (but not limited […]
Matthew Paul Agdanowski Yeates Group “The Development of an Imaging Scaffold for RNA Structural Analysis via Cryo-EM” and Janine Fu Loo Group “Targeting acyl-lysine modifications in the Rhodopseudomonas palustris proteome via diagnostic ions"
