"The development and targeting of epigenetic drugs for therapeutic benefit" Abstract: The talk will comprise two interconnected parts describing the development and targeting of epigenetic drugs for the treatment of disease. The development of bromodomain ligands for the treatment of disease: bromodomains, protein modules that ‘read’ of lysine acetylation state, have emerged as important therapeutic […]
“Releasing, or capturing, that is the question. Porous molecular materials” Porous materials are one important class where the shape and distribution of “empty” space throughout the framework is a main determinant for the resulting functionality. For instance, zeolites are available with many different pore size and geometries, which is the fundament of their wide spread […]
“Phosphorus-Oriented” Method Development and Total Synthesis Abstract: The lecture will describe the design, development and applications of new synthetic methods based upon phosphorus(V) reagents and catalysts. Topics will include catalytic halogenation, hydroxyl activation and the total synthesis of polychlorinated and trimeric phenol-derived natural products.
Recent Advancements in the Employment of Pd/Ni Catalyzed C-N Amide Cross-Coupling
“The Cell is a Bag of RNA”
“Ultrafast Synthesis: Leveraging Time-resolved Spectroscopy for Targeted Synthetic Control of Ultrafast Dynamics in Transition Metal-based Chromophores” Abstract: The interconversion of light and chemical energy is one of the most fundamental processes on Earth. Research on solar energy conversion, for example – which will ultimately lead to the next generation of solar energy technologies – has […]
“Choosing the right lens: Energy surfaces and chemical identity in the photodissociation of Na2+ in different solvent environments”
Novel chemotypes of kinase inhibitors for the potential treatment of recurrent cancers Abstract: Therapeutic resistance remains a critical issue in cancer treatment. While cancer patients who harbor dysregulated protein kinases benefit from the use of kinase inhibitors (KIs), many fail therapy and almost all patients become resistant to treatment, indicating a critical unmet need to […]
"Biophysical Studies of an RNA Virus particle and its Maturation: Insights into an Elegantly Programmed Nano-machine"
“Towards understanding the role of mass transport in electrocatalysis: the role of dimensionless analysis and multi-scale modeling”
Bridging the gap between well-defined and industrial catalysts via a molecular approach Industrial processes, in particular large-scale ones, mostly rely on heterogeneous catalysts. The search for more sustainable processes and the changes in environmental policies impose the continuous development of improved catalyst performances and catalytic processes, as well as the exploration of alternative routes. However, […]
