Combining Theory and Experiment to Develop Selective Three-Component Fe-Catalyzed Radical Cascade/Cross-Couplings
Abstract: Despite advances in high-throughput screening methods leading to a surge in the discovery of catalytic reactions, our knowledge of the molecular-level interactions in the rate- and selectivity-determining steps of catalytic reactions, especially those involving highly unstable and reactive open-shell intermediates, is rudimentary. These knowledge gaps prevent control, suppression or enhancement, of competing reaction channels that […]