Oxidation Reactivity of Pd(III) and Pd(IV) Complexes Supported by Flexible Multidentate Ligands

Seminar series
Inorganic Chemistry
Wed, Feb 27 4:30pm
Cram Conference Room, 3440 Mol Sci
Speaker Professor Liviu Mirica
Washington University (St. Louis)
Department of Chemistry

High-valent Pd complexes have been recently shown to play an important role in a number of organic transformations. Both dinuclear and mononuclear organometallic Pd(III) complexes have been proposed as active intermediates in the oxidative functionalization of C–H bonds and oxidatively induced C–C bond formation reactions, respectively. In this context, a series of stable mono- and dinuclear Pd(III) complexes supported by tetradentante and tridentate N-donor ligands have been synthesized and their stoichiometric and catalytic reactivity were investigated. In particular, we have studied the aerobic oxidation of organometallic Pd(II) complexes that yields detectable Pd(III) and Pd(IV) intermediates, followed by C-C or C-heteroatom bond formation reactions. These results suggest a possible catalytic cycle for the oxidative functionalization of C-H bonds using molecular oxygen as the oxidant. The relevance of Pd(III) species in various other organometallic reactions will also be discussed.