Enantioselective Chemical Synthesis Methods via Cooperative Catalysis: Design, Development and Application

Seminar series
Organic Colloquium
Thu, May 16 4:00pm
CS 24
Speaker Prof. Tom Snaddon
Indiana University
Department of Chemistry

Abstract: Our laboratory has embraced cooperative catalysis as a general framework for the design of new enantioselective reactions. Within this regime we have exploited cooperative Lewis base/transition metal catalysis as an effective means to control and direct both reaction partners during  bond construction. The versatility of this approach is such that each catalyst acts in an orthogonal manner, which permits the role and function of the metal center to be modified and tuned without compromising enantioselectivity. This seminar will describe our most recent efforts in asymmetric carbon–carbon  and carbon–nitrogen bond formation.