Break-it-to-Make-it Strategies for Chemical Synthesis Inspired by Complex Natural Products”

Seminar series
Organic Colloquium
Thu, Mar 4 4:00pm
Speaker Prof. Richmond Sarpong
University of California, Berkeley
Department of Chemistry

Abstract: Natural products continue to inspire and serve as the basis of new medicines. They also provide intricate problems that expose limitations in the strategies and methods employed in chemical synthesis. Several strategies and methods that have been developed in our laboratory and applied to the syntheses of architecturally complex diterpenoid alkaloids, indole alkaloids, and several Lycopodium alkaloids, will be discussed. In addition, new ways to employ C–C bond cleavage in synthesis will be presented (i.e., break-it-to-make-it strategies).