MACS Careers in Chemistry Seminar Series | Dr. Joyann Barber | Pfizer
2025-04-25 16:00 - 17:00 (America/Los_Angeles) | Young Hall 2033

Chem 248 Organic Chemistry Student Seminar: Miranda Li
2025-04-28 15:00 - 16:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Physical Chemistry Seminar 228: Prof. Andrew Musser
2025-04-28 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Jeffrey I. Zink Inorganic Chemistry Seminar Series – Prof. Mu-Hyun Baik
2025-04-29 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Chem 263: Seminars in Chemical Biology - Kaitlin Hartung
2025-04-29 16:00 - 17:30

Jeffrey I. Zink Inorganic Chemistry Seminar Series – Prof. Holger Kleinke
2025-04-30 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Houk-Jung Organic Colloquium (Chem 247)-- Prof. Donna Huryn
2025-05-01 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222
Title: Development of Allosteric Inhibitors of VCP/ p97 to Interrogate Novel Biology and Fuel Cancer Drug Discovery
Abstract: Clinical success in targeting the protein degradation pathway using proteasome inhibitors has spurred efforts to evaluate other aspects of this system as approaches to cancer therapy. Among those, the AAA ATPase, p97/ VCP, a master regulator of protein homeostasis, has recently emerged as a promising target. While there is pre-clinical validation that inhibition of p97 will have anti-tumor effects, a number of key questions still remain about its potential as a target for therapeutic efficacy, as well as its fundamental biology. Through the auspices of the National Cancer Institute’s (NCI’s) Chemical Biology Consortium, we developed multiple series of novel, potent allosteric inhibitors of p97. We solved the first high-resolution structure of p97 bound to an inhibitor using cryo-electron microscopy, and are using our molecules to decipher the complex biology of p97 and to develop new experimental therapeutics.

Dickerson Biochemistry Seminar Series – Theodosia Bartashevitch and Erin Kim – Midstream Presentation
2025-05-02 15:30 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

MACS Careers in Chemistry Seminar Series | Dr. John-Paul Cherry | Patterson + Sheridan LLP
2025-05-02 16:00 - 17:00 | Young Hall 2033

Physical Chemistry Seminar 228: Prof. Andrea Liu
2025-05-05 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Chem 263: Seminars in Chemical Biology - Jess Soule
2025-05-06 16:00 - 17:30 | Collaboratory Yoo Seminar & Conference Hall YH4222

Jeffrey I. Zink Inorganic Chemistry Seminar Series – Prof. Brandon Greene
2025-05-07 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Dickerson Biochemistry Seminar Series – Mai Abdusamad and Haley Marie De Ocampo – Midstream Presentation
2025-05-09 15:30 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Physical Chemistry Seminar 228: Prof. Songi Han
2025-05-12 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Faculty & Staff Event (Please do not schedule other department events on this day)
2025-05-13

Jeffrey I. Zink Inorganic Chemistry Seminar Series – Prof. Christopher Chang
2025-05-14 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Dickerson Biochemistry Seminar Series – Prof. Wendy Gilbert – Yale University
2025-05-16 15:30 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Physical Chemistry Seminar 228: Prof. Shenshen Wang
2025-05-19 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Chem 263: Seminars in Chemical Biology - Prof. Joseph Genereux
2025-05-20 16:00 - 17:30

Houk-Jung Organic Colloquium (Chem 247) -- Prof. Shauna Paradine
2025-05-22 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222
Title: Catalytic strategies for the selective construction of sp3-rich organic scaffolds
Abstract: The topological complexity of sp3-rich scaffolds imparts specific beneficial properties into organic small molecules and enables refined tuning of a molecule’s properties. However, this complexity amplifies both reactivity and selectivity challenges, making the development of versatile methods to construct and diversify these structures difficult. By combining fundamental advances in transition metal catalysis with organic synthesis, we aim to discover new reactions to solve unmet challenges in the construction of functional sp3-rich organic scaffolds. In one area, we have found that identifying “unconventional” ligand platforms for palladium catalysis leads to new reactivity and selectivity in olefin heteroannulation reactions. In another area, we have found that copper complexes can promote a range of oxidative radical addition reactions.

Dickerson Biochemistry Seminar Series – Ryan Howe and Jack Scully – Midstream Presentation
2025-05-23 15:30 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Chem 263: Seminars in Chemical Biology - Casey Morrison
2025-05-27 16:00 - 17:30

Dickerson Biochemistry Seminar Series – Prof. Anne-Claude Gingras – Lunenfeld-Tanenbaum Research Institute
2025-05-28 11:00 - 12:30

Jeffrey I. Zink Inorganic Chemistry Seminar Series – Prof. Eva Nichols
2025-05-28 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Dickerson Biochemistry Seminar Series – Reece Maxwell Pawlaczyk and Kyle Taylor– Midstream Presentation
2025-05-30 15:30 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Physical Chemistry Seminar 228: Prof. Jungwon Park
2025-06-02 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

CHEM 263: Seminars in Chemical Biology - Caitlyn Flick
2025-06-03 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

CHEM 263: Seminars in Chemical Biology - Prof. Nobuhiko Hosono
2025-06-03 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Jeffrey I. Zink Inorganic Chemistry Seminar Series – Prof. Catherine Drennan
2025-06-04 16:00 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222

Dickerson Biochemistry Seminar Series – Prof. Olivia Rissland– University of Colorado School of Medicine
2025-06-06 15:30 - 17:00 | Collaboratory Yoo Seminar & Conference Hall YH4222
