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X-ORIGINAL-URL:https://www.chemistry.ucla.edu
X-WR-CALDESC:Events for UCLA
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BEGIN:DAYLIGHT
TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20210314T100000
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TZOFFSETFROM:-0700
TZOFFSETTO:-0800
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DTSTART:20211107T090000
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210430T153000
DTEND;TZID=America/Los_Angeles:20210430T153000
DTSTAMP:20260615T120135
CREATED:20210415T233542Z
LAST-MODIFIED:20210415T233542Z
UID:13490-1619796600-1619796600@www.chemistry.ucla.edu
SUMMARY:Chem 268: Sean D. Gallaher and Einav Tayeb-Fligelman
DESCRIPTION:Sean D. Gallaher\, Ph.D.      \nMerchant Group \n“Prokaryotic-style polycistronic gene expression in eukaryotic green algae” \n~and~ \nEinav Tayeb-Fligelman\, Ph.D.     \nEisenberg Group \n“Modulation of Amyloid Formation of the Nucleoprotein of SARS-CoV-2”
URL:https://www.chemistry.ucla.edu/seminars/chem-268-sean-d-gallaher-and-einav-tayeb-fligelman/
CATEGORIES:Biochemistry,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210429T160000
DTEND;TZID=America/Los_Angeles:20210429T160000
DTSTAMP:20260615T120135
CREATED:20210329T184445Z
LAST-MODIFIED:20210329T184445Z
UID:13478-1619712000-1619712000@www.chemistry.ucla.edu
SUMMARY:New Synthetic Opportunities through Organic Photocatalysis”
DESCRIPTION:Abstract: Development of new synthetic strategies via organic photocatalysis in our group was described. Both photoacidic activity and photoredox activity of organic photocatalysts were discussed. A series of phenol-conjugated acridinium-based organic photoacids were rationally designed\, synthesized and studied alongside commercially available phenolic catalyst\, eosin Y. In the presence these photoacid catalysts and light\, synthetic glycals underwent activation and coupled with a range of alcohols to afford 2-deoxy-glycosides in good yields with excellent a-selectivity. Moreover\, a recent development of photo Lewis acid catalyst was described. In addition\, a photocatalytic N-radical cascade reactions were discussed\, including synthesis of pyrroloindolines\, rapid synthesis of flustramide B\, and remote allylation of uncativated sp3 C-H bonds.
URL:https://www.chemistry.ucla.edu/seminars/new-synthetic-opportunities-through-organic-photocatalysis/
CATEGORIES:Organic Colloquium,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210429T120000
DTEND;TZID=America/Los_Angeles:20210429T120000
DTSTAMP:20260615T120135
CREATED:20210422T205449Z
LAST-MODIFIED:20210422T205449Z
UID:13492-1619697600-1619697600@www.chemistry.ucla.edu
SUMMARY:Chem 218 Student Exit Seminar: Peiqi Wang
DESCRIPTION:“Van der Waals Integration beyond 2D Heterostructures” \n Abstract: The integration of dissimilar materials to form heterostructures with designable electronic interfaces is central in modern electronic devices and has thus been a long pursuit in material science. The traditional integration methods such as metal evaporation\, atomic layer deposition (ALD) and epitaxial growth typically rely on strong chemical bonds to combine the constituent materials. However\, this approach has limited freedom in integrating materials with distinct structural or chemical compositions due to the lattice matching or process compatibility requirements. Inspired by the variety of 2D van der Waals (vdW) heterostructures\, a physical transfer process exploiting the universal vdW force is proposed for damage-free integration of metal contact and 2D semiconductors to form pinning-free junctions approaching Schottky-Mott limit\, opening up vast freedom for creating a new generation of vdW-integrated devices beyond the reach of traditional heterostructures. This talk summarizes our recent progress of vdW integration of high-quality contacts of nearly arbitrary metals\, gate dielectrics and bulk semiconductors to create high-performance devices including 2D metal-oxide-semiconductor field-effect transistors (MOSFETs)\, metal-semiconductor FETs (MESFETs) and junction FETs (JFETs) based on bulk semiconductor β-Ga2O3\, which all exhibit atomically clean and electronically sharp interfaces with nearly ideal electronic functions. These devices extend vdW integration to a broader library of materials for creating high-performance electronic devices and explore the potential of vdW integration as a general and efficient approach for circuit-level integration.
URL:https://www.chemistry.ucla.edu/seminars/chem-218-student-exit-seminar-peiqi-wang/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210428T160000
DTEND;TZID=America/Los_Angeles:20210428T160000
DTSTAMP:20260615T120135
CREATED:20210323T222021Z
LAST-MODIFIED:20210323T222021Z
UID:13461-1619625600-1619625600@www.chemistry.ucla.edu
SUMMARY:Chem 278 Prof. Liu Research Group Seminar
DESCRIPTION:“Enhanced Gas Transport in Hybrid Bio-Inorganic CO2 and N2 Fixation Systems” \n Abstract: With the surge of intermittent\, renewable electricity\, the storage of excessive electricity and reduction of CO2 or N2 into value-added chemicals is of great significance for a sustainable society. One viable route is to construct a hybrid inorganic-biological system that converts electricity into chemical energy and reduces CO2/N2 into commodity chemicals. In this general approach\, water is electrochemically split into H2 and O2 and the yielded H2 is consumed by microbes as a reducing equivalent for CO2/N2 reduction. This system has demonstrated high efficiencies however\, the output of the commodity chemicals is limited by the supply of the reducing equivalent\, H2\, within the system. While we can electrochemically control the rate of H2 production\, the poor solubility of H2 in the aqueous environment results in a bottleneck. Here\, we demonstrate the addition of perfluorocarbon (PFC) nanoemulsions to increase H2 solubility and improve the kinetic rate of gas transport to the microbes for enhanced chemical production. With PFC nanoemulsions applied to our hybrid CO2 fixation system\, we maintained nearly 100% Faradaic efficiency over a range of applied current densities and increased the throughput 2.9 times at 2.0 mA/cm2. Similarly\, by adding varying percentages of PFC nanoemulsion to our N2 fixation system we were able to control the H2 and O2 concentrations in solution and enhance N2 fixation. Overall\, our research demonstrates the use of PFC nanoemulsions to enhance gas solubility and gas transport in aqueous solution for favorable reaction conditions and improved rates of chemical production.
URL:https://www.chemistry.ucla.edu/seminars/chem-278-prof-liu-research-group-seminar/
CATEGORIES:Inorganic Chemistry,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210427T160000
DTEND;TZID=America/Los_Angeles:20210427T160000
DTSTAMP:20260615T120135
CREATED:20210329T175414Z
LAST-MODIFIED:20210329T175414Z
UID:13476-1619539200-1619539200@www.chemistry.ucla.edu
SUMMARY:The Revolution Will Be Compartmentalized: Activity-Based and Cellular DNA-Encoded Library Technology
DESCRIPTION:Abstract: The NIH Molecular Libraries Program was founded to translate the discoveries of the Human Genome Project into therapeutics through a network of high-throughput screening (HTS) centers. A decade of discovery produced hundreds of probes—highly selective small molecules that modulate cellular function—but centralized HTS bears the same cost and infrastructure burdens of millennial DNA sequencing centers\, restricting access to the technology and therefore the rate of probe discovery. We are building a distributable drug discovery platform analogous to next-generation DNA sequencing based on ultra-miniaturized solid-phase DNA-encoded libraries and microfluidic instrumentation for scalable\, automated screening. I will overview chemical synthesis and microfluidic screening technology development efforts and describe their application to hit finding for two clinically relevant targets implicated in fibrosis and cancer. Looking toward the future\, we are exploring approaches that directly translate genomic sequence into bioactive chemical probes\, with the ultimate goal of fulfilling the originally promised pay dirt of the Human Genome Project.
URL:https://www.chemistry.ucla.edu/seminars/revolution-will-be-compartmentalized-activity-based-and-cellular-dna-encoded-library/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210426T160000
DTEND;TZID=America/Los_Angeles:20210426T160000
DTSTAMP:20260615T120135
CREATED:20210323T204418Z
LAST-MODIFIED:20210323T204418Z
UID:13453-1619452800-1619452800@www.chemistry.ucla.edu
SUMMARY:Chem 228: Prof. Andrew Pelling
DESCRIPTION:“Growing Cells on Apples\, LEGOs and Bread. Why Developing Unconventional Biomaterials Matters.”
URL:https://www.chemistry.ucla.edu/seminars/chem-228-prof-andrew-pelling/
CATEGORIES:Physical Chemistry Seminar,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210423T153000
DTEND;TZID=America/Los_Angeles:20210423T153000
DTSTAMP:20260615T120135
CREATED:20210415T232922Z
LAST-MODIFIED:20210415T232922Z
UID:13489-1619191800-1619191800@www.chemistry.ucla.edu
SUMMARY:Chem 268: Brendan Mahoney and Sudeepa Rajan
DESCRIPTION:Brendan Mahoney\, Ph.D.      \nClubb Group \n“Leveraging a new fluorescent fusion sensor reveals that bacterial chaperones associate with one another to rapidly transfer heme” \n~and~ \nSudeepa Rajan\, Ph.D.      \nReisler Group \n“Disassembly of fascin bundled actin filaments via their oxidation by Mical” \n  \n  \n 
URL:https://www.chemistry.ucla.edu/seminars/chem-268-brendan-mahoney-and-sudeepa-rajan/
CATEGORIES:Biochemistry,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210422T160000
DTEND;TZID=America/Los_Angeles:20210422T160000
DTSTAMP:20260615T120135
CREATED:20210329T184047Z
LAST-MODIFIED:20210329T184047Z
UID:13477-1619107200-1619107200@www.chemistry.ucla.edu
SUMMARY:Understanding the chemistry of volcanic RNA to treat cancer & COVID-19
DESCRIPTION:Abstract: N4-acetylcytidine is an ancient RNA modification catalyzed by an enzyme essential for human life. However\, its distribution\, dynamics\, and function remain mysterious. In this seminar I will introduce my group’s work developing chemical tools to investigate RNA acetylation\, why this led us to study an organism that thrives in solfatara (volcanic craters)\, and how we are using these fundamental studies to enable new therapeutic approaches.
URL:https://www.chemistry.ucla.edu/seminars/understanding-chemistry-volcanic-rna-treat-cancer-covid-19/
CATEGORIES:Organic Colloquium,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210422T120000
DTEND;TZID=America/Los_Angeles:20210422T120000
DTSTAMP:20260615T120135
CREATED:20210419T163230Z
LAST-MODIFIED:20210419T163230Z
UID:13491-1619092800-1619092800@www.chemistry.ucla.edu
SUMMARY:Chem 218 Student Exit Seminar: Fang-Chu Lin
DESCRIPTION:“Superparamagnetic Core/Shell Mesoporous Silica Nanoparticle for Magnetic Heating-Induced Anticancer Drug Delivery” \n ABSTRACT: Superparamagnetic iron oxide nanoparticles (SPION) generate heat in the presence of an alternating magnetic field (AMF) and are used in clinics to treat cancers. Mesoporous silica nanoparticles (SPION@MSN) embedded with SPION possess the advantageous features of both the SPION core and the shell\, i.e.\, localized magnetic heating and a high payload of various cargo molecules such as anticancer drugs\, respectively. This talk focuses on the development of SPION@MSNs as a heat-activated drug delivery platform in which the precise drug release can be directly controlled by using AMF. To expand our knowledge base in this application\, we first study the local heating mechanism of a SPION in suspension and in MSN. We carried out this investigation by using fluorescence depolarization based on detecting the mobility-dependent polarization anisotropy of two luminescence emission bands corresponded to the luminescent SPION core and the shell of the SPION@MSN. Utilizing the magnetic heating\, we then designed a magnetically activated and enzyme-responsive SPION@MSN vehicle with extra-large pores to deliver and release anticancer peptides on-demand. We demonstrate that a SPION core can act as a nano-heater to stimulate a cascade drug release and high tumor-targeting/inhibiting efficiency can be achieved. Altogether\, these works show the full potential of AMF-controlled core/shell nanoparticle vehicles for a more selected and precise dosage control.
URL:https://www.chemistry.ucla.edu/seminars/chem-218-student-exit-seminar-fang-chu-lin/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210421T160000
DTEND;TZID=America/Los_Angeles:20210421T160000
DTSTAMP:20260615T120135
CREATED:20210323T221133Z
LAST-MODIFIED:20210323T221133Z
UID:13460-1619020800-1619020800@www.chemistry.ucla.edu
SUMMARY:Chem 278: Prof. Jinyao Tang
DESCRIPTION:“Synthetic Nanorobot – from Individual Microswimmer to Active Swarm” \nAbstract: Over 60 years ago\, Prof. Richard Feynman envisioned that\, in principle\, machines could be made so tiny\, we can use them to construct matters from atomic/molecular scale; nanorobots can perform surgeries and deliver drugs at cellar level. Sixty years later\, the scientific community finds an inconvenient truth: many scientific challenges remain to be solved before nanodoctor can really enter clinics. In this talk\, I will start with the realization of the synthetic microswimmers with optical navigation capability to discuss how light can be used to manipulate designed semiconductor microparticles at high precision. I will then showcase how simple theoretical consideration in surface kinetics can help make microswimmer particles more biocompatible and operational in the biological environment. At last\, I will envision an intelligent\, active swarm system based on complex chemical interaction networks which may be used as a true nanosurgeon in the future.
URL:https://www.chemistry.ucla.edu/seminars/chem-278-prof-jinyao-tang/
CATEGORIES:Inorganic Chemistry,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210420T160000
DTEND;TZID=America/Los_Angeles:20210420T160000
DTSTAMP:20260615T120135
CREATED:20210329T175126Z
LAST-MODIFIED:20210329T175126Z
UID:13475-1618934400-1618934400@www.chemistry.ucla.edu
SUMMARY:Trehalose glycopolymer as an excipient for insulin stabilization: safety\, mechanism\, optimization\, and fluid properties
DESCRIPTION:Abstract: Biopharmaceutics are widely used to treat serious diseases\, but the architectural and chemical complexity that makes proteins good therapeutics renders them susceptible to degradation and aggregation during manufacturing\, transportation\, and storage. Loss of intact biopharmaceutics causes patient under-dosing as well as adverse reactions. With the growth of biopharmaceuticals coming to market\, the need increases for benign excipients to stabilize proteins against environmental stresses without posing a safety concern. A class of glycopolymers bearing a pendant trehalose\, a natural sugar\, were developed by our group and demonstrated the ability to stabilize a range of biopharmaceuticals. However\, this research area had not yet explored the trehalose polymer for safety\, mechanism of stabilization\, physical properties\, or potential optimization. This talk focuses on the ongoing efforts to expand our knowledge base in applying the methacrylate trehalose polymer as an excipient to formulate biopharmaceuticals. In particular\, I will highlight the glycopolymer’s benign immunogenic\, excretion\, and biodistribution behaviors as well as how proteins are unaffected in vivo by the polymer. Next\, because the mechanism by which proteins are stabilized as well as the conformation in which they are stabilized affects their onset of activity\, I will show how the glycopolymer stabilizes insulin. Due to the importance of patient comfort and compliance\, I will finally present my research into the fluid properties of the glycopolymer\, optimization of insulin formulations\, and optimized formulations properties. Altogether\, this work shows specifically how insulin is stabilized by the methacrylate trehalose polymer and\, more broadly\, that the glycopolymer can be broadly applied as an excipient to stabilize therapeutic macromolecules safely and without significantly changing the in vivo response or physical properties.
URL:https://www.chemistry.ucla.edu/seminars/trehalose-glycopolymer-excipient-insulin-stabilization-safety-mechanism-optimization-and/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210419T160000
DTEND;TZID=America/Los_Angeles:20210419T160000
DTSTAMP:20260615T120135
CREATED:20210323T204216Z
LAST-MODIFIED:20210323T204216Z
UID:13452-1618848000-1618848000@www.chemistry.ucla.edu
SUMMARY:Chem 228: Prof. Hirofumi Tanaka
DESCRIPTION:“Reservoir computing device composed by chemical dynamics”
URL:https://www.chemistry.ucla.edu/seminars/chem-228-prof-hirofumi-tanaka/
CATEGORIES:Physical Chemistry Seminar,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210416T153000
DTEND;TZID=America/Los_Angeles:20210416T153000
DTSTAMP:20260615T120135
CREATED:20210325T211113Z
LAST-MODIFIED:20210325T211113Z
UID:13468-1618587000-1618587000@www.chemistry.ucla.edu
SUMMARY:Chem 268: Dylan Valencia
DESCRIPTION:Quinlan Group \n“Biochemical Characterization of Mammalian Formin FHOD3 in Cardiomyocytes”
URL:https://www.chemistry.ucla.edu/seminars/chem-268-dylan-valencia/
CATEGORIES:Biochemistry,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210415T120000
DTEND;TZID=America/Los_Angeles:20210415T120000
DTSTAMP:20260615T120135
CREATED:20210408T223431Z
LAST-MODIFIED:20210408T223431Z
UID:13488-1618488000-1618488000@www.chemistry.ucla.edu
SUMMARY:Electrophotocatalysis with a trisaminocyclopropenium ion
DESCRIPTION:Abstract: This lecture will describe some recent developments in the area of electrophotocatalysis\, with a particular focus on a trisaminocyclopropenium (TAC) ion catalyst developed by our group.
URL:https://www.chemistry.ucla.edu/seminars/electrophotocatalysis-trisaminocyclopropenium-ion/
CATEGORIES:Organic Colloquium,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210415T100000
DTEND;TZID=America/Los_Angeles:20210415T100000
DTSTAMP:20260615T120135
CREATED:20210331T001119Z
LAST-MODIFIED:20220410T011049Z
UID:12320-1618480800-1618480800@www.chemistry.ucla.edu
SUMMARY:2020-2021 Sigman Symposium
DESCRIPTION:The UCLA Molecular Biology Institute (MBI) will hold the 2020-2021 Sigman Symposium in honor of Professor David Sigman (1939-2001)\, who was an internationally renowned UCLA professor of chemistry and biological chemistry who illuminated the molecular mechanisms by which enzymes catalyze biological reactions and was one of the founding members of the MBI. \n2020-2021 Sigman Award Honoree: \nProfessor Catherine DrennanDepartments of Chemistry and BiologyMassachusetts Institute of Technology andthe Howard Hughes Medical Institute \nKenote Address: “Shake\, Rattle\, & Roll:Capturing Snapshots of Ribonucleotide Reductase in Action” \nSymposium Schedule – Thursday\, April 15\, 2021 – 10 am to 1:30 pm \n\nTribute to David Sigman: Prof. Steven Clarke\nGuest Speaker: Prof. Douglas Rees (Caltech):“The Ns and Outs of Nitrogen Fixation”\nKeynote introduction/award presentation: Prof. Keriann Backus\nKeynote address: Prof. Catherine Drennan\nPoster Session and Poster Prize Announcement\n\nPosteSession: The poster session will feature immersion in an 8-bit world complete with “walking” around to interact with poster presenters and attendees\, games\, and more while providing an opportunity to share your science with our awardee\, members of the UCLA community\, and have a chance to win one of our poster prizes! Poster prizes will include Best Poster Prizes (up to four $250 prizes) and Honorable mention prizes (up to four $100 prizes) and will be selected with an audience voting component. All UCLA students and postdocs studying in any area of biology or chemistry are eligible to submit. To present a poster please fill out the google form with your poster title by Friday\, April 2\, 2021 and submit a png\, jpeg\, or gif image file of your poster to SigmanSymposium2021@gmail.com  by Tuesday April 6\, 2021. Poster prize winners will be announced after the poster session in a gather.town award ceremony.    \nFor more information about the Sigman Symposium or poster session please visit the MBI website or email SigmanSymposium2021@gmail.com. 
URL:https://www.chemistry.ucla.edu/seminars/2020-2021-sigman-symposium/
ATTACH;FMTTYPE=image/jpeg:https://www.chemistry.ucla.edu/wp-content/uploads/2021/03/drennan-400x400-2_0.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210413T160000
DTEND;TZID=America/Los_Angeles:20210413T160000
DTSTAMP:20260615T120135
CREATED:20210329T174856Z
LAST-MODIFIED:20210329T174856Z
UID:13474-1618329600-1618329600@www.chemistry.ucla.edu
SUMMARY:Perfluorocarbon nanomaterials as theranostic delivery vehicles
DESCRIPTION:Abstract: Perfluorocarbon nanoemulsions\, droplets of fluorous solvent stabilized by a polymeric amphiphile dispersed in water\, are an intriguing platform for drug delivery. The fluorous phase is biocompatible\, has a high dissolved oxygen content\, and is both lipophobic and hydrophobic\, preventing the leaching of payloads. Here\, we describe the use of perfluorocarbon nanoemulsions as a drug delivery platform in which the payload can be easily modified. First\, we utilize the high oxygen solubility of perfluorocarbons to perform photodynamic therapy\, a treatment modality that requires oxygen\, photosensitizer\, and light to produce cytotoxic reactive oxygen species. Next\, we deliver pDNA solubilized by noncovalent fluorous tags\, resulting in the transfection of cells. Lastly\, a panel of polymeric amphiphiles were studied to determine design properties such as size\, stability\, payload release\, cellular uptake and protein corona. With these design principles PFC nanoemulsions can be tailored to a desired application.
URL:https://www.chemistry.ucla.edu/seminars/perfluorocarbon-nanomaterials-theranostic-delivery-vehicles/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210413T130000
DTEND;TZID=America/Los_Angeles:20210413T130000
DTSTAMP:20260615T120135
CREATED:20210129T165333Z
LAST-MODIFIED:20210129T165333Z
UID:13439-1618318800-1618318800@www.chemistry.ucla.edu
SUMMARY:NSF Center for Integrated Catalysis Webinar Series
DESCRIPTION:The NSF Center for Integrated Catalysis is delighted to announce that it will be hosting a monthly webinar series. The next webinar of this series will be held on Tuesday\, April 13th\, 2021 at 1:00 PM.  We are pleased to invite all students\, postdocs\, faculty\, and staff.
URL:https://www.chemistry.ucla.edu/seminars/nsf-center-integrated-catalysis-webinar-series-5/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210412T160000
DTEND;TZID=America/Los_Angeles:20210412T160000
DTSTAMP:20260615T120135
CREATED:20210323T203220Z
LAST-MODIFIED:20210323T203220Z
UID:13450-1618243200-1618243200@www.chemistry.ucla.edu
SUMMARY:Chem 228: Prof. Chanmin Su
DESCRIPTION:“Scanning probe microscopy for physical and chemical property characterizations at the nanoscale”
URL:https://www.chemistry.ucla.edu/seminars/chem-228-prof-chanmin-su/
CATEGORIES:Physical Chemistry Seminar,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210407T160000
DTEND;TZID=America/Los_Angeles:20210407T160000
DTSTAMP:20260615T120135
CREATED:20210323T215118Z
LAST-MODIFIED:20210323T215118Z
UID:13459-1617811200-1617811200@www.chemistry.ucla.edu
SUMMARY:Chem 278: Prof. Charles W. Machan
DESCRIPTION:“Earth-Abundant Molecular Catalyst System for the Reduction of Dioxygen and Carbon Dioxide” \n Abstract: The steady increase in anthropogenic carbon dioxide (CO2) emissions and corresponding atmospheric concentrations continues to generate interest in using CO2 as a liquid fuel and commodity chemical precursor. The conversion of CO2 has the dual benefit of addressing its associated negative environmental effects and the diminishing supply of petrochemical feedstocks. At the heart of efficient reductive transformations are proton-coupled electron transfer (PCET) reactions\, where electrons and protons move in a concerted way to mitigate kinetic and thermodynamic penalties. Mechanistic understanding of these reactions can inform the design of optimized catalyst structures with improved activity and selectivity for specific products. Another cathodic reaction\, the electrocatalytic reduction of dioxygen (O2)\, has relevance to the development of more efficient fuel cells and can be similarly optimized through fundamental knowledge of the underlying PCET reactions. Molecular systems are well-positioned to provide a better understanding of these reactions because of the relative fidelity with which they can be characterized\, as well as the possibility for systematic testing of structure-function relationships through iterative molecular design. In addition to developing new Fe-\, Mn-\, and Cr-based molecular electrocatalysts for these reactions\, we are exploring the use of redox mediators and flow-based electrochemical reactors to understand how these reactions can be scaled relative to comparable heterogeneous systems.
URL:https://www.chemistry.ucla.edu/seminars/chem-278-prof-charles-w-machan/
CATEGORIES:Inorganic Chemistry,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210405T160000
DTEND;TZID=America/Los_Angeles:20210405T160000
DTSTAMP:20260615T120135
CREATED:20210323T203536Z
LAST-MODIFIED:20210323T203536Z
UID:13451-1617638400-1617638400@www.chemistry.ucla.edu
SUMMARY:OCDS Seminar: Prof. Karin Chumbimuni-Torres
DESCRIPTION:“Electrochemical biosensors for viruses and bacteria: new approaches and challenges”
URL:https://www.chemistry.ucla.edu/seminars/ocds-seminar-prof-karin-chumbimuni-torres/
CATEGORIES:Physical Chemistry Seminar,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210402T153000
DTEND;TZID=America/Los_Angeles:20210402T153000
DTSTAMP:20260615T120135
CREATED:20210325T204556Z
LAST-MODIFIED:20210325T204556Z
UID:13467-1617377400-1617377400@www.chemistry.ucla.edu
SUMMARY:Chem 268: Prof. Hernan Garcia
DESCRIPTION:“Dissecting Transcriptional Dynamics in Development One Burst at a Time”
URL:https://www.chemistry.ucla.edu/seminars/chem-268-prof-hernan-garcia/
CATEGORIES:Biochemistry,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210331T160000
DTEND;TZID=America/Los_Angeles:20210331T160000
DTSTAMP:20260615T120135
CREATED:20210323T213721Z
LAST-MODIFIED:20210323T213721Z
UID:13458-1617206400-1617206400@www.chemistry.ucla.edu
SUMMARY:Chem 278: Prof. Wenliang Huang
DESCRIPTION:“f-Block metal-arene interactions: from inverse sandwiches to redox chemistry” \nAbstract: Recent years have witnessed the breakthrough of identifying unusual oxidation states of f-block elements in molecular compounds such as divalent rare earth metals and actinides\, as well as tetravalent terbium and praseodymium. By taking advantage of the symmetry and energy match between the f/d orbitals of low-valent f-block ions and π* orbitals of arenes\, we synthesized a series of metal arene complexes featuring an inverse-sandwich structure. We found that δ bonds are responsible for the unusual stability of the tetranionic arene anions in such compounds. Moreover\, f-block ions show a significant covalent character\, and the extent of covalent interaction increases according to the order: rare earth metals < thorium < uranium. Inspired by these metal-arene δ bonding interactions\, as well as the traditional π-donor character of arene ligands\, we designed a tripodal-type tris(amide) ligand system featuring an arene anchor. We anticipated that the amphiphilic nature of the arene backbone may support both low and high valent f-block metal centers. This strategy allowed us to stabilize multiple oxidation states of f-block metals with a single ligand and opened up new avenues in the redox chemistry of these ions.
URL:https://www.chemistry.ucla.edu/seminars/chem-278-prof-wenliang-huang/
CATEGORIES:Inorganic Chemistry,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210319T130000
DTEND;TZID=America/Los_Angeles:20210319T130000
DTSTAMP:20260615T120135
CREATED:20210308T180314Z
LAST-MODIFIED:20210308T180314Z
UID:13449-1616158800-1616158800@www.chemistry.ucla.edu
SUMMARY:NSF Center for Integrated Catalysis Webinar Series
DESCRIPTION:“Invention of Catalysts for Synthesis of New Plastics” \n Abstract: This presentation will begin with a brief discussion of the properties of polyethylene and the synthesis of various forms of polyethylene via early metal catalysts and via free radical processes. Following this short discussion\, I will discuss our thought processes in developing late metal olefin polymerization catalysts and focus particularly on the chemistry of Ni(II) and Pd(II) diimine-derived catalysts. The talk will finish with a discussion of issues surrounding copolymerization of ethylene and polar vinyl monomers and a mechanistic dissection of the copolymerization of ethylene with vinyl trialkoxysilanes using both Pd(II) and Ni(II) diimine catalysts.
URL:https://www.chemistry.ucla.edu/seminars/nsf-center-integrated-catalysis-webinar-series-6/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210318T120000
DTEND;TZID=America/Los_Angeles:20210318T120000
DTSTAMP:20260615T120135
CREATED:20210225T175009Z
LAST-MODIFIED:20210225T175009Z
UID:13445-1616068800-1616068800@www.chemistry.ucla.edu
SUMMARY:Chem 218 Student Exit Seminar: Arundhati Deshmukh
DESCRIPTION:“Tuning the Excitonic Properties of 2-Dimensional Molecular Aggregates across the Visible and Shortwave Infrared” \n Molecular aggregates are non-covalent self-assemblies of chromophores wherein transition dipole moments of individual molecules couple coherently over long distances\, forming delocalized excitons. This imparts exciting photophysical properties such as extreme blue or red shifts (seen in H- or J-aggregates respectively)\, narrow linewidths and high molar absorptivities. We modulate the transition dipole couplings within an aggregate via molecular packing\, topology\, and disorder in order to tune and explore new photophysical behaviors. In this talk\, I will discuss the unusual situation that arises from 2D transition dipole coupling in sheet-like aggregates. In addition to traditional H- and J-aggregation\, we find a new case of ‘I-aggregation’ which shows intermediate characteristics of H- and J-aggregates. I will also describe how we use thermodynamics of self-assembly to control the aggregate packing and thereby\, tune excitonic properties. Using a three-component equilibrium model\, I will lay down general principles for selectively stabilizing H- or J-aggregates\, allowing us to construct a library of 2D J-aggregates with absorptions spanning the visible and shortwave infrared (SWIR) regions. Finally\, I will show how subtle differences in chromophore structures within this library modulate the aggregate packing and eventually lead to distinct excitonic band pictures\, that can be experimentally probed using temperature dependent spectroscopy. Overall\, this work establishes molecular aggregation as a tunable avenue for accessing unusual photophysical properties and thus\, opens up organic chromophores to new functionalities including SWIR imaging\, plexitonics\, and telecommunications.
URL:https://www.chemistry.ucla.edu/seminars/chem-218-student-exit-seminar-arundhati-deshmukh/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210312T153000
DTEND;TZID=America/Los_Angeles:20210312T153000
DTSTAMP:20260615T120135
CREATED:20210104T172741Z
LAST-MODIFIED:20210104T172741Z
UID:13405-1615563000-1615563000@www.chemistry.ucla.edu
SUMMARY:CANCELLED - Chem 268: Prof. Hernan Garcia
DESCRIPTION:“Dissecting Transcriptional Dynamics in Development One Burst at a Time”
URL:https://www.chemistry.ucla.edu/seminars/cancelled-chem-268-prof-hernan-garcia/
CATEGORIES:Biochemistry,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210311T130000
DTEND;TZID=America/Los_Angeles:20210311T130000
DTSTAMP:20260615T120135
CREATED:20210304T164257Z
LAST-MODIFIED:20210304T164257Z
UID:13447-1615467600-1615467600@www.chemistry.ucla.edu
SUMMARY:CIC Careers in Green Chemistry Seminar Series
DESCRIPTION:The Center for Integrated Catalysis is hosting a new seminar series called the “Careers in Green Chemistry.” With these webinars\, we aim to bring speakers from a wide variety of careers\, linked through green chemistry\, to come talk about their current job as well as the career path that led them to that position. We are pleased to invite all students\, postdocs\, and faculty.
URL:https://www.chemistry.ucla.edu/seminars/cic-careers-green-chemistry-seminar-series/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210311T120000
DTEND;TZID=America/Los_Angeles:20210311T120000
DTSTAMP:20260615T120135
CREATED:20210120T173102Z
LAST-MODIFIED:20210120T173102Z
UID:13430-1615464000-1615464000@www.chemistry.ucla.edu
SUMMARY:Chem 218 Student Exit Seminar: David Reilley
DESCRIPTION:Chemical Change in Protein Molecular Dynamics: Developing Computational Tools for Metal Binding and pH Sensitivity \n Molecular dynamics (MD) is a powerful tool to study atomic scale changes in proteins underpinning biological pathways. However\, simulations traditionally sample a fixed chemical state and struggle to achieve quantitatively accurate energies\, making comparisons of different chemical ensembles challenging. Hybrid quantum mechanical-classical approaches (QM/MM) can provide accurate energies for small regions of interest\, such as the active site\, but cannot readily capture all chemical transformations relevant to protein function. This talk will focus on developments and applications of hybrid methods to study the metal binding preferences and pH sensitivity of proteins. We will first discuss how we used QM/DMD combined with a competitive metal affinity method\, a semi-empirical thermodynamic cycle\, to obtain relative binding affinities for a wide range of metals to human serum transferrin (hTF)\, an iron transport protein. Our results clarified a mechanism for promiscuous metal binding in hTF and the role the protein may play in transport of non-physiological and potentially cytotoxic metals. We will then discuss the development of a titration feature for constant pH simulations with DMD (titr-DMD). Our method features stochastic protonation and deprotonation of amino acids while treating solvent implicitly\, which makes it computationally efficient compared to other techniques. We successfully benchmarked titr-DMD on experimentally verified pH-dependent conformational changes. Our work demonstrates the utility of molecular dynamics\, and QM/DMD in particular\, to study chemical changes in proteins with good accuracy and speed.
URL:https://www.chemistry.ucla.edu/seminars/chem-218-student-exit-seminar-david-reilley/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210310T160000
DTEND;TZID=America/Los_Angeles:20210310T160000
DTSTAMP:20260615T120135
CREATED:20210120T172051Z
LAST-MODIFIED:20210120T172051Z
UID:13425-1615392000-1615392000@www.chemistry.ucla.edu
SUMMARY:Chem 278: Prof. Long Luo
DESCRIPTION:Electrifying Inorganic and Organic Synthesis \nAbstract: Electrochemical synthesis is a powerful tool for formulating functional materials and moleculesbecause it offers an additional level of control over the synthesis relative to its chemical counterpart by fine-tuning mass transfer\, potential\, or current. Electrochemical synthesis also allows the convenient analysis of chemical reaction thermodynamics and kinetics using the current signal generated during the electrochemical synthesis. In this talk\, two recent advancements in electrochemical synthesis will be presented: (1) Electrochemical gelation of nanoparticles and (2) Alternating current electrolysis for organic synthesis. 
URL:https://www.chemistry.ucla.edu/seminars/chem-278-prof-long-luo/
CATEGORIES:Inorganic Chemistry,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210310T120000
DTEND;TZID=America/Los_Angeles:20210310T120000
DTSTAMP:20260615T120135
CREATED:20210304T164531Z
LAST-MODIFIED:20210304T164531Z
UID:13448-1615377600-1615377600@www.chemistry.ucla.edu
SUMMARY:Chem 218 Student Exit Seminar: Wenfei Li
DESCRIPTION:Developing Highly Efficient Electronic Structure Theory Methods for Large Scale Simulations \n Electronic structure simulations are now becoming an indispensable tool in chemistry research. The overall goal is to develop methods that give accurate results without sacrificing efficiency. In our group\, we incorporate various computational techniques to drastically reduce the cost of simulations. This allows us to run large scale simulations that were not previously possible. Our major innovation is stochastic quantum chemistry\, where we replaced the summation over thousands of deterministic orbitals to an average over much smaller number of stochastic orbitals\, and sometimes only a few suffices. This leads to significant increase in efficiency. In this seminar\, I will talk about my two projects under the stochastic quantum chemistry framework. The first project involved developing an embedding stochastic framework\, where a sub-system of interest is treated using deterministic orbitals\, while the rest of the system is treated using stochastic orbitals. This way\, we can selectively reduce the stochastic errors associated with that sub-system. The second project involved finding an optimal DFT starting point for our stochasticGW code. Apart from that\, I will also introduce our orthogonal projector augmented wave package. Compared with the norm-conserving pseudopotential approach\, the PAW method will allow a lower kinetic energy cutoff\, hence greatly enhances the efficiency of electronic structure theory simulations.
URL:https://www.chemistry.ucla.edu/seminars/chem-218-student-exit-seminar-wenfei-li/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210308T160000
DTEND;TZID=America/Los_Angeles:20210308T160000
DTSTAMP:20260615T120135
CREATED:20210120T182725Z
LAST-MODIFIED:20210120T182725Z
UID:13435-1615219200-1615219200@www.chemistry.ucla.edu
SUMMARY:Chem 228: Peter Dahlberg\, Ph.D.
DESCRIPTION:“Combining cryogenic single-molecule fluorescence measurements and CryoEM: New methods with applications from biology to physical chemistry”
URL:https://www.chemistry.ucla.edu/seminars/chem-228-peter-dahlberg-phd/
CATEGORIES:Physical Chemistry Seminar,Seminars
END:VEVENT
END:VCALENDAR