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DTSTART;TZID=America/Los_Angeles:20230223T110000
DTEND;TZID=America/Los_Angeles:20230223T120000
DTSTAMP:20260614T015709
CREATED:20221215T223825Z
LAST-MODIFIED:20230202T192222Z
UID:26935-1677150000-1677153600@www.chemistry.ucla.edu
SUMMARY:Special Physical Chemistry Seminar 228: Jörg Enderlein
DESCRIPTION:Enderlein Flyer Updated \nTitle: Metal and Graphene Induced Energy Transfer \nAbstract:   Metal-Induced Energy Transfer (MIET) Imaging is a recently developed method [1] that allows for nanometer resolution along the optical axis. It is based on the fact that\, when placing a fluorescent molecule close to a metal\, its fluorescence properties change dramatically\, due to electromagnetic coupling of its excited state to surface plasmons in the metal. This is very similar to Förster Resonance Energy Transfer (FRET) where the fluorescence properties of a donor are changed by the proximity of an acceptor that can resonantly absorb energy emitted by the donor. In particular\, one observes a strongly modified lifetime of its excited state. This coupling between an excited emitter and a metal film is strongly dependent on the emitter’s distance from the metal. We have used this effect for mapping the basal membrane of live cells with an axial accuracy of ~3 nm. The method is easy to implement and does not require any change to a conventional fluorescence lifetime microscope; it can be applied to any biological system of interest\, and is compatible with most other super-resolution microscopy techniques that enhance the lateral resolution of imaging [2-4]. Moreover\, it is even applicable to localizing individual molecules [5-6]\, thus offering the prospect of three-dimensional single-molecule localization microscopy with nanometer isotropic resolution for structural biology [7]. I will also present latest developments of MIET where we use a single layer of graphene instead of a metal film that allows for increasing the spatial resolution down to a few Ångströms [8-10].
URL:https://www.chemistry.ucla.edu/events/physical-chemistry-seminar-228-jorg-enderlein/
LOCATION:Young Hall 2033
CATEGORIES:Physical Chemistry Seminar,Special Seminars
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DTSTART;TZID=America/Los_Angeles:20230223T120000
DTEND;TZID=America/Los_Angeles:20230223T130000
DTSTAMP:20260614T015709
CREATED:20230120T212342Z
LAST-MODIFIED:20230120T212342Z
UID:27373-1677153600-1677157200@www.chemistry.ucla.edu
SUMMARY:Chem 218 Student Exit Seminar: Anthony Sica
DESCRIPTION:
URL:https://www.chemistry.ucla.edu/events/chem-218-student-exit-seminar-anthony-sica/
LOCATION:Mani L. Bhaumik Centennial Collaboratory\, 607 Charles E. Young Dr.\, East\, Los Angeles\, CA\, 90095\, United States
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20230223T160000
DTEND;TZID=America/Los_Angeles:20230223T170000
DTSTAMP:20260614T015709
CREATED:20230207T211913Z
LAST-MODIFIED:20230207T211913Z
UID:28073-1677168000-1677171600@www.chemistry.ucla.edu
SUMMARY:Houk-Jung Organic Colloquium 247: Emily Balskus
DESCRIPTION:Balskus Flyer\n\nTitle: Deciphering the Human Microbiome with Chemistry\n\n\n\n\n\n\n\n\n\n\n\n\n\nAbstract: The human body is colonized by trillions of microorganisms that exert a profound influence on human biology\, in part by providing functional capabilities that extend beyond those of host cells. In particular\, there is growing evidence linking chemical processes carried out by the human gut microbiome to diseases such as colorectal cancer. However\, we still do not understand the vast majority of the molecular mechanisms underlying this phenomenon. Major obstacles faced in surmounting this knowledge gap include the difficulty linking functions associated with the human gut microbiota to specific microbial enzymes and the challenge of controlling these activities in complex microbial communities. This talk will discuss my lab’s efforts to characterize gut microbial metabolic activities that are linked to colorectal cancer\, including a gut microbial genotoxin called colibactin. Gaining a molecular understanding of cancer-associated gut microbial activities will not only help to elucidate the mechanisms by which these organisms contribute to carcinogenesis but should also enable efforts to treat and prevent disease by manipulating this microbial community.
URL:https://www.chemistry.ucla.edu/events/houk-jung-organic-colloquium-247-emily-balskus/
LOCATION:Mani L. Bhaumik Centennial Collaboratory\, 607 Charles E. Young Dr.\, East\, Los Angeles\, CA\, 90095\, United States
CATEGORIES:Organic Colloquium
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