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DTSTART:20220313T100000
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DTSTART;TZID=America/Los_Angeles:20221017T150000
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CREATED:20220921T214630Z
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UID:24045-1666018800-1666018800@www.chemistry.ucla.edu
SUMMARY:Organic Student Seminar 248: Erin Bucci
DESCRIPTION:
URL:https://www.chemistry.ucla.edu/seminars/organic-student-seminar-2022-10-10/
LOCATION:Mani L. Bhaumik Centennial Collaboratory\, 607 Charles E. Young Dr.\, East\, Los Angeles\, CA\, 90095\, United States
CATEGORIES:Organic,Seminars
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20221017T160000
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DTSTAMP:20260614T044504
CREATED:20220901T223828Z
LAST-MODIFIED:20220921T230329Z
UID:23188-1666022400-1666026000@www.chemistry.ucla.edu
SUMMARY:Physical Chemistry Seminar 228: Christy Landes
DESCRIPTION:Prof. Landes Flyer \nTitle: Towards Predictive Protein Separations: Imaging Protein Dynamics at Nanoscale Interfaces \nAbstract: Recent efforts by our group and others have shown the promise of applying single molecule methods to link mechanistic detail about protein adsorption to macroscale observables. When we study one molecule at a time\, we eliminate ensemble averaging\, thereby accessing underlying heterogeneity. However\, we must develop new methods to increase information content in the resulting low density and low signal-to-noise data and to improve space and time resolution. \nI will highlight recent advances in super-resolution microscopy for quantifying the physics and chemistry that occur between target proteins and stationary phase supports during chromatographic separations. My discussion will concentrate on the newfound ability of super-resolved single protein spectroscopy to inform theoretical parameters via quantification of adsorption-desorption dynamics\, protein unfolding\, and nano-confined transport. Additionally\, I will discuss using phase manipulation to encode temporal and 3D spatial information\, and the opportunities and challenges associated with such imaging methods.
URL:https://www.chemistry.ucla.edu/events/physical-chemistry-seminar-228-christy-landes/
LOCATION:Mani L. Bhaumik Centennial Collaboratory\, 607 Charles E. Young Dr.\, East\, Los Angeles\, CA\, 90095\, United States
CATEGORIES:Physical Chemistry Seminar
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