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X-ORIGINAL-URL:https://www.chemistry.ucla.edu
X-WR-CALDESC:Events for UCLA
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TZID:America/Los_Angeles
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TZOFFSETFROM:-0800
TZOFFSETTO:-0700
TZNAME:PDT
DTSTART:20210314T100000
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DTSTART:20211107T090000
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BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210209T130000
DTEND;TZID=America/Los_Angeles:20210209T130000
DTSTAMP:20260618T165944
CREATED:20210120T173300Z
LAST-MODIFIED:20210120T173300Z
UID:13431-1612875600-1612875600@www.chemistry.ucla.edu
SUMMARY:NSF Center for Integrated Catalysis Webinar Series
DESCRIPTION:The NSF Center for Integrated Catalysis is delighted to announce that it will be hosting a monthly webinar series. The next webinar of this series will be held on Tuesday\, February 9th\, 2021 at 1:00 PM.  We are pleased to invite all students\, postdocs\, faculty\, and staff.
URL:https://www.chemistry.ucla.edu/seminars/nsf-center-integrated-catalysis-webinar-series-4/
CATEGORIES:Other,Seminars
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20210209T160000
DTEND;TZID=America/Los_Angeles:20210209T160000
DTSTAMP:20260618T165944
CREATED:20210120T175055Z
LAST-MODIFIED:20210120T175055Z
UID:13432-1612886400-1612886400@www.chemistry.ucla.edu
SUMMARY:Small molecule inhibitors of 15-prostaglandin dehydrogenase promote tissue repair and regeneration
DESCRIPTION:Abstract: Prostaglandin E2 promotes tissue repair and regeneration in multiple tissues. Small molecule inhibitors of the PGE2-degrading enzyme\, 15-prostaglandin dehydrogenase\, could elevate PGE2 levels in vivo with applications in multiple disease contexts. We have discovered two chemical series of enzyme inhibitors. Medicinal chemistry efforts have led to sub-nM inhibitors with excellent bioavailability and physicochemical properties. Lead compounds demonstrate activity in mouse models of inflammatory bowel disease\, recovery from bone marrow transplantation\, and neurodegeneration.
URL:https://www.chemistry.ucla.edu/seminars/small-molecule-inhibitors-15-prostaglandin-dehydrogenase-promote-tissue-repair-and/
CATEGORIES:Organic Colloquium,Seminars
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