Bruinsma, Robijn


WebsiteHome URL
Division
Physical
Title
Faculty
Professor
Specialties
Theoretical Condensed Matter

Contact Information

Email
Office
3-120 Knudsen
(310) 825-8539

Short Biography

  • Vrije Universiteit, Amsterdam, B.S. in Physics.(1974)
  • Rijks-Universiteit Utrecht, M.S. in Physics (1976)
  • University of Southern California., Ph.D. in Physics (1976)

Research Interest

My current work concerns the application of theoretical physics and numerical modeling to molecular biology. Emphasis is on the following areas:

  • Numerical Simulation of Active Proteins and of Gene Transcription.
  • Self-Assembly of Viruses
  • Self-Assembly of DNA and the Physics of Chromatin.
  • Electrostatics of DNA and electrical transport along DNA.
  • Adhesion of vesicles and cells.

Honors & Awards

  • Pierre et Marie Curie Visiting Professorship (E.S.P.C.I.).(1994)
  • Rothschild Foundation Fellowship.(1996)
  • Fellow American Physical Society
  • Distinguished Lecturer, College de France (1999)

Publications

Selected Publications

  • Klapstein KD, Bruinsma R
    RecA force generation of hydrolysis waves
    BIOPHYS J 82 (1): 581 Part 2 JAN 2002

  • Bruinsma R, Rondelez F, Levine A
    Flow-controlled growth in Langmuir monolayers
    EUR PHYS J E 6 (3): 191-200 NOV 2001

  • Bruinsma R, Sackmann E
    Bioadhesion and the dewetting transition
    CR ACAD SCI IV-PHYS 2 (6): 803-815 AUG 2001

  • Bruinsma R
    Liquid crystals of polyelectrolyte networks
    PHYS REV E 63 (6): art. no. 061705 Part 1 JUN 2001

  • Schiessel H, Gelbart WM, Bruinsma R
    DNA folding: Structural and mechanical properties of the two-angle model for chromatin
    BIOPHYS J 80 (4): 1940-1956 APR 2001

  • Kosztin I, Bruinsma R, Schulten K Conformational changes and force generation in the molecular switch protein H-Ras BIOPHYS J 80 (1): 1005 Part 2 JAN 2001

  • Marx S, Guttenberg Z, Bruinsma R, et al.
    Measuring receptor-ligand unbinding forces with magnetic beads
    BIOPHYS J 80 (1): 1006 Part 2 JAN 2001

  • Bruinsma R, Gruner G, D'Orsogna MR, et al.
    Fluctuation-facilitated charge migration along DNA
    PHYS REV LETT 85 (20): 4393-4396 NOV 13 2000

  • Guttenberg Z, Bausch AR, Hu B, et al.
    Measuring ligand-receptor unbinding forces with magnetic beads: Molecular leverage
    LANGMUIR 16 (23): 8984-8993 NOV 14 2000

  • Schiessel H, Rudnick J, Bruinsma R, et al.
    Organized condensation of worm-like chains
    EUROPHYS LETT 51 (2): 237-243 JUL 2000

  • Klapstein K, Bruinsma R
    RecA force generation by hydrolysis waves
    J BIOL CHEM 275 (21): 16073-16083 MAY 26 2000

  • Bruinsma R, Behrisch A, Sackmann E
    Adhesive switching of membranes: Experiment and theory
    PHYS REV E 61 (4): 4253-4267 Part B APR 2000

  • Nardi J, Bruinsma R, Sackman E
    Vesicles as osmotic motors
    PHYS REV LETT 82 (25): 5168-5171 JUN 21 1999

  • Rudnick J, Bruinsma R
    DNA-protein cooperative binding through variable-range elastic coupling
    BIOPHYS J 76 (4): 1725-1733 APR 1999

  • Levine A, Ramaswamy S, Frey E, et al.
    Screened and unscreened phases in sedimenting suspensions
    PHYS REV LETT 81 (26): 5944-5947 DEC 28 1998

  • Luz Z, Weger M, Bruinsma R, et al.
    Shlomo Alexander - Obituary
    PHYS TODAY 51 (12): 73-74 DEC 1998

  • Nardi J, Bruinsma R, Sackmann E
    Adhesion-induced reorganization of charged fluid membranes
    PHYS REV E 58 (5): 6340-6354 Part B NOV 1998

  • Bruinsma R
    Electrostatics of DNA cationic lipid complexes: isoelectric instability
    EUR PHYS J B 4 (1): 75-88 JUL 1998

  • Albersdorfer A, Bruinsma R, Sackmann E
    Force spectroscopy on adhesive vesicles
    EUROPHYS LETT 42 (2): 227-231 APR 15 1998

  • Ahsan A, Rudnick J, Bruinsma R
    Elasticity theory of the B-DNA to S-DNA transition
    BIOPHYSICS J74(1): 132-137 JAN 1998

  • Julicher F, Bruinsma R
    Motion of RNA polymerase along DNA: A stochastic model
    BIOPHYS J 74 (3): 1169-1185 MAR 1998

  • Prost J, Manneville JB, Bruinsma R
    Fluctuation-magnification of non-equilibrium membranes near a wall
    EUR PHYS J B 1 (4): 465-480 FEB 1998

  • Bruinsma R, Mashl J
    Long-range electrostatic interaction in DNA cationic lipid complexes
    EUROPHYS LETT 41 (2): 165-170 JAN 15 1998

  • Martin JI, Wang ZG, Zuckerman D, et al.
    Forces between surfaces with weakly end-adsorbed polymers
    J PHYS II 7 (8): 1111-1121 AUG 1997

  • Nardi J, Feder T, Bruinsma R, et al.
    Electrostatic adhesion between fluid membranes: Phase separation and blistering (vol 37, pg 371, 1997)
    EUROPHYS LETT 38 (2): 159-160 APR 10 1997

  • Bruinsma R
    Les liaisons dangereuses: Adhesion molecules do it statistically
    P NATL ACAD SCI USA 94 (2): 375-376 JAN 21 1997

  • Bekiranov S, Bruinsma R, Pincus P
    Solution behavior of polyethylene oxide in water as a function of temperature and pressure
    PHYS REV E 55 (1): 577-585 Part B JAN 1997

  • Gelbart WM, Bruinsma R
    Compositional-mechanical instability of interacting mixed lipid membranes
    PHYS REV E 55 (1): 831-835 Part B JAN 1997

  • Bruinsma R
    Rheology and shape transitions of vesicles under capillary flow
    PHYSICA A 234 (1-2): 249-270 DEC 15 1996

  • Bruinsma R, Pincus P

    Protein aggregation in membranes
    CURR OPIN SOLID ST M 1 (3): 401-406 JUN 1996

  • Lammert PE, Prost J, Bruinsma R
    Ion drive for vesicles and cells
    J THEOR BIOL 178 (4): 387-391 FEB 21 1996

  • Prost J, Bruinsma R
    Shape fluctuations of active membranes
    EUROPHYS LETT 33 (4): 321-326 FEB 1 1996

  • Bruinsma R.
    Theory of hydrodynamic convection in soap films
    PHYSICA A 216 (1-2): 59-76 JUN 1 1995

  • Zuckerman D, Bruinsma R.
    Statistical-mechanics of membrane adhesion by reversible molecular-bonds
    PHYS REV LETT 74 (19): 3900-3903 MAY 8 1995

  • Rudnick J, Bruinsma R
    Shape of domains in 2-dimensional systems ­ virtual singularities and a generalized wulff construction
    PHYS REV LETT 74 (13): 2491-2494 MAR 27 1995

  • Schwartz DK, Knobler CM, Bruinsma R.
    Direct observation of langmuir monolayer flow-through a channel
    PHYS REV LETT 73 (21): 2841-2844 NOV 21 1994

  • Bruinsma R, Goulian M, Pincus P.
    Self-assembly of membrane junctions
    BIOPHYS J 67 (2): 746-750 AUG 1994

  • Bruinsma R, Prost J
    Fluctuation forces and the devils staircase of ferroelectric smectic C-asterisk-S
    J PHYS II 4 (7): 1209-1219 JUL 1994

  • Bruinsma R, Rabin Y
    Mesoscopic physics of swollen polymer networks ­ statics and dynamics
    PHYS REV E 49 (1): 554-569 JAN 1994

  • Prost J, Bruinsma R, Tournilhac F
    Theory of longitudinal ferroelectric smectics
    J PHYS II 4 (1): 169-187 JAN 1994

  • Bekiranov S, Bruinsma R, Pincus p
    A primitive model for single-chain aqueous-solution behavior of peo under pressure
    EUROPHYS LETT 24 (3): 183-188 OCT 20 1993

  • Rabin Y, Pekarski P, Bruinsma R
    Charge effects on density-fluctuations in stretched gels
    EUROPHYS LETT 24 (2): 145-149 OCT 10 1993

  • Lederman M, Selinger JV, Bruinsma R, et al.
    Dynamics of the diluted ising antiferromagnet in the (h,t) plane
    PHYS REV B 48 (6): 3810-3819 AUG 1 1993

  • Zuckerman D, Bruinsma R
    Chaotic drainage of soap films
    ABSTR PAP AM CHEM S 206: 179-COLL Part 1 AUG 22 1993

  • Goulian M, Bruinsma R, Pincus P
    Long-range forces in heterogeneous fluid membranes (vol 22, pg 145, 1993)
    EUROPHYS LETT 23 (2): 155-155 JUL 10 1993

  • Larson RG, Winey KI, Patel SS, et al.
    The rheology of layered liquids - lamellar block-copolymers and smectic liquid-crystals
    RHEOL ACTA 32 (3): 245-253 MAY-JUN 1993

  • Shi J, Bruinsma R, Bishop AR
    Excitations of the one-dimensional, 2-band peierls-hubbard model at 3/4 filling in the large-u limit
    PHYS REV B 47 (15): 9181-9188 APR 15 1993

  • Goulian M, Bruinsma R, Pincus P
    Long-range forces in heterogeneous fluid membranes
    EUROPHYS LETT 22 (2): 145-150 APR 10 1993

  • Rabin Y, Pekarski P, Bruinsma R
    Fluctuations in strained polymer gels
    ABSTR PAP AM CHEM S 205: 126-PMSE Part 2 MAR 28 1993

  • Martin T, Bruinsma R, Platzman PM
    Quantum-theory of surface-adsorption
    PHYS REP 223 (3): 135-181 JAN 1993

  • Bruinsma R, Dimeglio JM, Quere D. et al.
    Formation of soap films from polymer-solutions
    LANGMUIR 8 (12): 3161-3167 DEC 1992

  • Rabin Y, Bruinsma R
    Strain effects on thermal fluctuations in soft solids ­butterfly patterns
    EUROPHYS LETT 20 (1): 79-85 SEP 1 1992

  • Lederman M, Selinger JV, Bruinsma R, et al.
    Low-temperature dynamics of a diluted ising antiferromagnet
    PHYS REV LETT 68 (13): 2086-2089 MAR 30 1992

  • Bruinsma R
    Elasticity and excitations of minimal crystals
    J PHYS II 2 (3): 425-451 mar 1992

  • Bruinsma R, Rabin Y
    Shear-flow enhancement and suppression of fluctuations in smectic liquid-crystals
    PHYS REV A 45 (2): 994-1008 JAN 15 1992

  • Eklund EA, Bruinsma R, Rudnick J, et al.
    Submicron-scale surface roughening induced by ion-bombardment
    PHYS REV LETT 67 (13): 1759-1762 SEP 23 1991

  • Bruinsma R
    Growth instabilities of vesicles
    J PHYS II 1 (8): 995-1012 AUG 1991

  • Shi J, Bruinsma R, Bishop AR
    Theory of vanadium dioxide
    SYNTHETIC MET 43 (1-2): 3527-3530 JUN 7 1991

  • Martin T, Bruinsma R, Platzman PM
    Adsorption of positronium on metal-surfaces - theory
    PHYS REV B 43 (8): 6466-6473 MAR 15 1991